Evidence map›Paper›PMID 28840121›Full record

ArticleInternational journal of genomics2017

A Pilot Genome-Wide Association Study in Postmenopausal Mexican-Mestizo Women Implicates the RMND1/CCDC170 Locus Is Associated with Bone Mineral Density.

Marisela Villalobos-Comparán, Rogelio F Jiménez-Ortega, Karol Estrada, Alma Y Parra-Torres, Anahí González-Mercado, Nelly Patiño, Manuel Castillejos-López, Manuel Quiterio, Juan Carlos Fernandez-López, Bertha Ibarra and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Marisela Villalobos-ComparánConsorcio de Genómica Computacional, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Rogelio F Jiménez-OrtegaLaboratorio de Genómica del Metabolismo Óseo, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.ORCID 0000-0002-3976-4759
Karol EstradaStatistical Genetics, Biogen, Cambridge, MA, USA.
Alma Y Parra-TorresLaboratorio de Genómica del Metabolismo Óseo, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Anahí González-MercadoCentro Universitario en Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, JAL, Mexico.
Nelly PatiñoInstituto Nacional de Medicina Genómica, Mexico City, Mexico.
Manuel Castillejos-LópezUnidad de Vigilancia Epidemiológica Hospitalaria, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico.
Manuel QuiterioCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, MOR, Mexico.
Juan Carlos Fernandez-LópezConsorcio de Genómica Computacional, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Bertha IbarraCentro Universitario en Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, JAL, Mexico.
Sandra Romero-HidalgoConsorcio de Genómica Computacional, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.
Jorge SalmerónCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, MOR, Mexico.
Rafael Velázquez-CruzLaboratorio de Genómica del Metabolismo Óseo, Instituto Nacional de Medicina Genómica, Mexico City, Mexico.ORCID 0000-0003-4515-0777
National Institute of Genomic Medicine · MXMexican Social Security Institute · MXBiogen (United States) · USInstituto Nacional de Enfermedades Respiratorias · MXInstituto Nacional de Salud Pública · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To identify genetic variants influencing bone mineral density (BMD) in the Mexican-Mestizo population, we performed a GWAS for femoral neck (FN) and lumbar spine (LS) in Mexican-Mestizo postmenopausal women. In the discovery sample, 300,000 SNPs were genotyped in a cohort of 411 postmenopausal women and seven SNPs were analyzed in the replication cohort (

Identifiers

PMID28840121
PMCPMC5559934
OpenAlexW2745142012

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.