ArticleSurgical neurology international2017
Epidural scarring after lumbar disc surgery: Equivalent scarring with/without free autologous fat grafts.
Article in Surgical neurology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Postoperative Epidural Fibrosis Prevention: Which Is Better-Autologous Fat versus Gelfoam.Asian spine journal · 2022Article
- Survey of lumbar discectomy practices: 10 years in the making.Journal of spine surgery (Hong Kong) · 2020Article
- Development of Endoscopic Spine Surgery for Healthy Life: To Provide Spine Care for Better, for Worse, for Richer, for Poorer, in Sickness and in Health.Neurospine · 2020Article
- Pirfenidone inhibits epidural scar fibroblast proliferation and differentiation by regulating TGF-β1-induced Smad-dependent and -independent pathways.American journal of translational research · 2019Article
- Analysis of risk factors and postoperative predictors for recurrent lumbar disc herniation.Surgical neurology international · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo limit epidural fibrosis and prevent scar formation/nerve tethering that may contribute to chronic postoperative pain; some surgeons have utilized epidural autologous fat grafts following lumbar microdiscectomy.
methodsWe investigated the correlation between post-microdiscectomy epidural scarring [including select magnetic resonance imaging (MRI) studies] and clinical outcomes in 36 patients operated for symptomatic. MRI documented L4-L5 and L5-S1 disk herniations with (18 patients) and without (18 patient) the application of free fat grafts. In addition, histological evaluation of the original fat grafts was performed in 4 patients requiring additional surgery.
resultsWe found no clear association between the use of autologous graft fats and the clinical outcomes in this study.
conclusionIn this preliminary study involving only 36 patients, the prospective randomized use of free autologous fat grafts did not appear to influence outcomes following microdiscectomy.
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