ArticleInterface focus2017
Genetic, epigenetic and exogenetic information in development and evolution.
Article in Interface focus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Developmental synergistic information.Theory in biosciences = Theorie in den Biowissenschaften · 2026Article
- Alternative splicing dynamically regulates common carp embryogenesis under thermal stress.BMC genomics · 2024Article
- The Role of Information in Evolutionary Biology.Acta biotheoretica · 2023Article
- A generalised approach to the study and understanding of adaptive evolution.Biological reviews of the Cambridge Philosophical Society · 2023Article
- Epigenetic Molecular Mechanisms in Insects.Neotropical entomology · 2020Review
- The hierarchically mechanistic mind: an evolutionary systems theory of the human brain, cognition, and behavior.Cognitive, affective & behavioral neuroscience · 2019Review
- Why developmental niche construction is not selective niche construction: and why it matters.Interface focus · 2017Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The idea that development is the expression of information accumulated during evolution and that heredity is the transmission of this information is surprisingly hard to cash out in strict, scientific terms. This paper seeks to do so using the sense of information introduced by Francis Crick in his sequence hypothesis and central dogma of molecular biology. It focuses on Crick's idea of precise determination. This is analysed using an information-theoretic measure of causal specificity. This allows us to reconstruct some of Crick's claims about information in transcription and translation. Crick's approach to information has natural extensions to non-coding regions of DNA, to epigenetic marks, and to the genetic or environmental upstream causes of those epigenetic marks. Epigenetic information cannot be reduced to genetic information. The existence of biological information in epigenetic and exogenetic factors is relevant to evolution as well as to development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.