Evidence map›Paper›PMID 28839629›Full record

ReviewFrontline gastroenterology2012

Parenteral methotrexate for patients with Crohn's disease: how to develop a high-quality and safe self-administration service.

Iona Coltart, Laura Blackmore, Jane Caisley, Adam Harris

Abstract readReview
In one paragraph

Review in Frontline gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iona ColtartDepartment of Gastroenterology, The Tunbridge Wells Hospital, Tunbridge Wells, UK.
Laura BlackmoreDepartment of Gastroenterology, The Tunbridge Wells Hospital, Tunbridge Wells, UK.
Jane CaisleyDepartment of Pharmacy, The Tunbridge Wells Hospital, Tunbridge Wells, UK.
Adam HarrisDepartment of Gastroenterology, The Tunbridge Wells Hospital, Tunbridge Wells, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parenteral methotrexate is recommended for patients with Crohn's disease who have failed treatment with thiopurines. There is no good evidence for the use of oral methotrexate, yet patients frequently receive this due to the difficulties associated with prescribing and administering an unlicensed, cytotoxic drug. We present our experience of developing a local service to provide our patients with the option to self-administer parenteral methotrexate in a safe and structured manner at home.

Identifiers

PMID28839629
PMCPMC5517247

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.