Evidence map›Paper›PMID 28839372›Full record

ArticlePharmacognosy magazine

Quassinoids from the Root of

Nguyen Huu Tung, Takuhiro Uto, Nguyen Thanh Hai, Gang Li, Yukihiro Shoyama

Open access · greenAbstract read
In one paragraph

Article in Pharmacognosy magazine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Quassinoids as Promising Anti-cancer Agents.Current medicinal chemistry · 2025
    Review
  3. Article
  4. [UPLC-Q-TOF-MS/MS combined with network pharmacology for exploring antiinflammatory mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Quassinoids from the Roots ofMolecules (Basel, Switzerland) · 2021
    Article
  9. A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study onSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Review
  10. The Powdered Root ofNutrients · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nguyen Huu TungDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki 859-3298, Japan.
Takuhiro UtoDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki 859-3298, Japan.
Nguyen Thanh HaiDepartment of Pharmacy, School of Medicine and Pharmacy, Vietnam National University, Hanoi, Vietnam.
Gang LiDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki 859-3298, Japan.
Yukihiro ShoyamaDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki 859-3298, Japan.
Vietnam National University, Hanoi · VNNagasaki International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe roots of

objectiveThe objective of this study was to study on antiproliferative compounds from the root of MATERIALS AND

methodsColumn chromatography was used to separate individual compounds, spectroscopic data including nuclear magnetic resonances and mass spectrometry were analyzed to determine the chemical structure of the isolates and for biological testing, antiproliferative activity of compounds was tested on seven human cancer cell lines (KATO III, HCT-15, Colo205, HepG2, PC-3, Jurkat, HL-60) by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method.

resultsNine quassinoids including a new C

conclusionThe current study reveals one new quassinoid glycoside and the potential active component (eurycomanone) from SUMMARY: Nine quassinoids (1-9) including one new quassinoid glycoside (9) and eight known ones were isolated from the roots of

Indexed as

Antiproliferative activityEurycoma longifolialeukemia cellsquassinoidSimaroubaceae

Identifiers

PMID28839372
PMCPMC5551365
OpenAlexW2738578481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.