Evidence map›Paper›PMID 28839248›Full record

ArticleScientific reports2017

Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China.

Hongfei Lou, Siyuan Ma, Yan Zhao, Feifei Cao, Fei He, Zhongyan Liu, Jean Bousquet, Chengshuo Wang, Luo Zhang, Claus Bachert

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05510024 (Radiofrequency Ablation of Bilateral Inferior Turbinate Followed by Subcutaneous Immunotherapy Trial for Severe House Dust Mite-sensitized Allergic Rhinitis), which is not on this map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05510024 nanot yet recruitingnot on this mapstarted 2022, after this paper: background citation

Radiofrequency Ablation of Bilateral Inferior Turbinate Followed by Subcutaneous Immunotherapy Trial for Severe House Dust Mite-sensitized Allergic Rhinitis

TypeinterventionalSponsorEye & ENT Hospital of Fudan UniversityRan2022 to 2026Enrolled392ConditionsAllergic Rhinitis Due to House Dust MiteArmsRadiofrequency ablation of bilateral inferior turbinate followed by subcutaneous immunotherapy, SCIT
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 115 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
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  7. Efficacy ofJournal of asthma and allergy · 2026
    Article
  8. Changes of Pollen Allergens in Northern China.International archives of allergy and immunology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Landscape of Aeroallergen Sensitization in Asia.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
  13. Asia Pacific allergy · 2025
    Article
  14. Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Hongfei LouDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730, China.
Siyuan MaDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730, China.
Yan ZhaoBeijing Key Laboratory of nasal diseases, Beijing Institute of Otolaryngology, Beijing, 100005, China.
Feifei CaoDepartment of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730, China.
Fei HeBeijing Key Laboratory of nasal diseases, Beijing Institute of Otolaryngology, Beijing, 100005, China.
Zhongyan LiuBeijing Key Laboratory of nasal diseases, Beijing Institute of Otolaryngology, Beijing, 100005, China.
Jean BousquetDepartment of Respiratory Diseases, University Hospital, Hôpital Arnaud de Villeneuve, Montpellier, France.
Chengshuo WangDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730, China.
Luo ZhangDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730, China. dr.luozhang@139.com.
Claus BachertUpper Airways Research Laboratory, Department of Oto-Rhino-Laryngology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Beijing Institute of Neurosurgery · CNBeijing Tongren Hospital · CNCapital Medical University · CNGhent University Hospital · BEHôpital Arnaud de Villeneuve · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimization of skin prick test (SPT) panels, especially in view of significant differences in sensitizations patterns within different geographical areas, is an unmet need within China. Our aim was to assess the patterns and clinical relevance of aeroallergen sensitizations in allergic rhinitis (AR) and define the minimal battery of SPT allergens, classified according to the Köppen-Geiger climate map. Overall, 7148 subjects with self-reported AR completed a standard questionnaire and were assessed for sensitization to relevant allergens by SPT. 6340 (88.7%) patients had at least one positive skin prick reaction, and demonstrated unique sensitization patterns by stratification with age, gender, and geographic region. Sensitization to house dust mites (HDM) was highest in south China, whereas the three most prevalent aeroallergens were mugwort, ragweed and dandelion pollen in north-west China. Higher sensitization rates and multiple sensitizations were associated with AR comorbidities. Eight allergens (Der f, mugwort, Blatella, hazel, goosefoot, Penicillium notatum, animal dander and Der p) allowed identification >96% of sensitized subjects in central China. Differences in optimal panels were observed between regions, with five to six allergens being sufficient for north-east, north-west and south China. These SPT panels may provide a cost-effective tool for screening sensitized patients in China.

Indexed as

AerosolsSelf ReportAdolescentAdultAgedAllergensChildChinaComorbidityFemaleHumansImmunizationMaleMiddle AgedPopulation SurveillancePrevalenceAerosolsAllergens

Identifiers

PMID28839248
PMCPMC5570894
OpenAlexW2747063016

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.