ArticleScientific reports2017
Spatiotemporal changes in regularity of gamma oscillations contribute to focal ictogenesis.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Comparison of volume- and surface-based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia.Epilepsia · 2026Article
- Ectopic action potentials in regular spiking neurons in the anesthetized mouse.Journal of neurophysiology · 2026Article
- Article
- Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia.Epilepsia open · 2026Article
- Network-guided resection of magnetic resonance imaging-negative mesial temporal epilepsy using gamma oscillation regularity-based transfer entropy analysis.Surgical neurology international · 2026Article
- Personalizing Seizure Detection for Individual Patients by Optimal Selection of EEG Signals.Sensors (Basel, Switzerland) · 2025Article
- Sample entropy analysis with high-density electroencephalography for non-invasive evaluation of hemispheric language dominance.Surgical neurology international · 2025Article
- GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα.Frontiers in pharmacology · 2025Article
- Effectiveness of perampanel for focal seizures determined by interictal gamma oscillation regularity analysis.Epilepsia open · 2024Article
- Utilizing Excitatory and Inhibitory Activity Derived from Interictal Intracranial Electroencephalography as Potential Biomarkers for Epileptogenicity.Neurologia medico-chirurgica · 2024Article
- Evaluating cortical excitatory and inhibitory activity through interictal intracranial electroencephalography in mesial temporal lobe epilepsy.Frontiers in neuroscience · 2024Article
- Interictal gamma oscillation regularity analysis and susceptibility-weighted imaging on focal epilepsy cases with alcohol use disorders.Surgical neurology international · 2024Article
- Neurophysiological assessment of cortical activity in DEPDC5- and NPRL3-related epileptic mTORopathies.Orphanet journal of rare diseases · 2023Article
- Cognitive and emotional regulation processes of spontaneous facial self-touch are activated in the first milliseconds of touch: Replication of previous EEG findings and further insights.Cognitive, affective & behavioral neuroscience · 2022Article
- Low EEG Gamma Entropy and Glucose Hypometabolism After Corpus Callosotomy Predicts Seizure Outcome After Subsequent Surgery.Frontiers in neurology · 2022Article
- Visualization of ictal networks using gamma oscillation regularity correlation analysis in focal motor epilepsy: Illustrative cases.Surgical neurology international · 2022Article
- Distinct effects of heterogeneity and noise on gamma oscillation in a model of neuronal network with different reversal potential.Scientific reports · 2021Article
- Epileptogenic zone localization using intraoperative gamma oscillation regularity analysis in epilepsy surgery for cavernomas: patient series.Journal of neurosurgery. Case lessons · 2021Article
- The Onset of Interictal Spike-Related Ripples Facilitates Detection of the Epileptogenic Zone.Frontiers in neurology · 2021Article
- Intraoperative epileptogenic network visualization using gamma oscillation regularity correlation analysis in epilepsy surgery.Surgical neurology international · 2021Article
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6 authors.
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Abstract
In focal ictogenesis, gamma oscillations (30-70 Hz) recorded by electroencephalography (EEG) are related to the epileptiform synchronization of interneurons that links the seizure onset zone (SOZ) to the surrounding epileptogenic zone. We hypothesized that the synchronization of interneurons could be detected as changes in the regularity of gamma oscillation rhythmicity. We used multiscale entropy (MSE) analysis, which can quantify the regularity of EEG rhythmicity, to investigate how the regularity of gamma oscillations changes over the course of a seizure event. We analyzed intracranial EEG data from 13 pediatric patients with focal cortical dysplasia. The MSE analysis revealed the following characteristic changes of MSE score (gamma oscillations): (1) during the interictal periods, the lowest MSE score (the most regular gamma oscillations) was always found in the SOZ; (2) during the preictal periods, the SOZ became more similar to the epileptogenic zone as the MSE score increased in the SOZ (gamma oscillations became less regular in the SOZ); and (3) during the ictal periods, a decreasing MSE score (highly regular gamma oscillations) propagated over the epileptogenic zone. These spatiotemporal changes in regularity of gamma oscillations constitute an important demonstration that focal ictogenesis is caused by dynamic changes in interneuron synchronization.
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