ArticleScientific reports2017
Metabolomic compounds identified in Piriformospora indica-colonized Chinese cabbage roots delineate symbiotic functions of the interaction.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 65 citations in OpenAlex.
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- A pipeline for validation of Serendipita indica effector-like sRNA suggests cross-kingdom communication in the symbiosis with Arabidopsis.Journal of experimental botany · 2025Article
- Reduced content of gamma-aminobutyric acid enhances resistance to bacterial wilt disease in tomato.Plant biotechnology journal · 2025Article
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- The Root-Colonizing EndophyteInternational journal of molecular sciences · 2023Article
- Diversity and potential plant growth promoting capacity of seed endophytic bacteria of the holoparasite Cistanche phelypaea (Orobanchaceae).Scientific reports · 2023Article
- Reprogramming of Fundamental miRNA and Gene Expression during the Barley-Journal of fungi (Basel, Switzerland) · 2022Article
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- Metabolomics-Driven Mining of Metabolite Resources: Applications and Prospects for Improving Vegetable Crops.International journal of molecular sciences · 2022Review
- Piriformospora indica recruits host-derived putrescine for growth promotion in plants.Plant physiology · 2022Article
- Article
- EndophyticFrontiers in microbiology · 2022Article
- The Change in Fatty Acids and Sugars Reveals the Association between Trifoliate Orange and Endophytic Fungi.Journal of fungi (Basel, Switzerland) · 2021Article
- Putative markers for the detection of early-stage bladder cancer selected by urine metabolomics.BMC bioinformatics · 2021Article
- Metabolomics and transcriptomics to decipher molecular mechanisms underlying ectomycorrhizal root colonization of an oak tree.Scientific reports · 2021Article
- Harnessing symbiotic plant-fungus interactions to unleash hidden forces from extreme plant ecosystems.Journal of experimental botany · 2020Review
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Root colonization by endophytic fungus Piriformospora indica facilitating growth/development and stress tolerance has been demonstrated in various host plants. However, global metabolomic studies are rare. By using high-throughput gas-chromatography-based mass spectrometry, 549 metabolites of 1,126 total compounds observed were identified in colonized and uncolonized Chinese cabbage roots, and hyphae of P. indica. The analyses demonstrate that the host metabolomic compounds and metabolite pathways are globally reprogrammed after symbiosis with P. indica. Especially, γ-amino butyrate (GABA), oxylipin-family compounds, poly-saturated fatty acids, and auxin and its intermediates were highly induced and de novo synthesized in colonized roots. Conversely, nicotinic acid (niacin) and dimethylallylpyrophosphate were strongly decreased. In vivo assays with exogenously applied compounds confirmed that GABA primes plant immunity toward pathogen attack and enhances high salinity and temperature tolerance. Moreover, generation of reactive oxygen/nitrogen species stimulated by nicotinic acid is repressed by P. indica, and causes the feasibility of symbiotic interaction. This global metabolomic analysis and the identification of symbiosis-specific metabolites may help to understand how P. indica confers benefits to the host plant.
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