Evidence map›Paper›PMID 28839192›Full record

ArticleScientific reports2017

Indole-based perenosins as highly potent HCl transporters and potential anti-cancer agents.

Laura A Jowett, Ethan N W Howe, Vanessa Soto-Cerrato, Wim Van Rossom, Ricardo Pérez-Tomás, Philip A Gale

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 63 citations in OpenAlex.

  1. Near-Infrared Triggered Anion Transport Induces Cancer Cell Death.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Hemi-Indigiosin: A pH and Red-Light Responsive Transmembrane HCl Transporter.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Review
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  10. Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021
    Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Laura A JowettSchool of Chemistry (F11), The University of Sydney, 2006, Sydney, NSW, Australia.
Ethan N W HoweSchool of Chemistry (F11), The University of Sydney, 2006, Sydney, NSW, Australia.
Vanessa Soto-CerratoDepartment of Pathology and Experimental Therapeutics, Cancer Cell Biology Research Group, University of Barcelona, Barcelona, Spain.
Wim Van RossomChemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
Ricardo Pérez-TomásDepartment of Pathology and Experimental Therapeutics, Cancer Cell Biology Research Group, University of Barcelona, Barcelona, Spain.
Philip A GaleSchool of Chemistry (F11), The University of Sydney, 2006, Sydney, NSW, Australia. philip.gale@sydney.edu.au.ORCID 0000-0001-9751-4910
The University of Sydney · AUUniversitat de Barcelona · ESUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prodigiosin is one of the most potent anion transporters in lipid bilayer membranes reported to date. Inspired by the structure of this natural product, we have recently designed and synthesised a new class of H

Indexed as

Hydrochloric AcidIndolesAntineoplastic AgentsBiological TransportCell Line, TumorCell SurvivalDose-Response Relationship, DrugHumansInhibitory Concentration 50Ion TransportMembrane Transport ProteinsModels, MolecularMolecular ConformationMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsHydrochloric AcidindoleIndolesMembrane Transport Proteins

Identifiers

PMID28839192
PMCPMC5570892
OpenAlexW2746063323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.