ArticleScientific reports2017
Melittin-induced alterations in morphology and deformability of human red blood cells using quantitative phase imaging techniques.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Antimicrobial peptides in the era of resistance: integrating AI-driven design, host-microbe interactions, and nanotechnological delivery.Frontiers in microbiology · 2026Review
- Bee Venom Melittin Modulates In Vivo Water Permeability of Red Blood Cells: Microscopic andMolecules (Basel, Switzerland) · 2025Article
- Structure-Function Insights into Frog Skin Peptides Reveal Potent Inhibition of West Nile Virus Entry.International journal of molecular sciences · 2025Article
- Label-Free Digital Holotomography Reveals Ibuprofen-Induced Morphological Changes to Red Blood Cells.ACS nanoscience Au · 2023Article
- Erythrocyte Membrane Biophysical Changes Mediated by Pooled Immunoglobulin G and Hematin: Electrokinetic and Lipid Peroxidation Studies.Membranes · 2023Article
- A new therapeutic approach for bone metastasis in colorectal cancer: intratumoral melittin.The journal of venomous animals and toxins including tropical diseases · 2022Article
- Correlation of dynamic membrane fluctuations in red blood cells with diabetes mellitus and cardiovascular risks.Scientific reports · 2021Article
- Effects of osmolality and solutes on the morphology of red blood cells according to three-dimensional refractive index tomography.PloS one · 2021Article
- Holotomography: Refractive Index as an Intrinsic Imaging Contrast for 3-D Label-Free Live Cell Imaging.Advances in experimental medicine and biology · 2021Article
- Effect of dilution of canine blood samples on the specificity of saline agglutination tests for immune-mediated hemolysis.Journal of veterinary internal medicine · 2020Article
- The Effect of Bee Venom Peptides Melittin, Tertiapin, and Apamin on the Human Erythrocytes Ghosts: A Preliminary Study.Metabolites · 2020Article
- Revisiting the Interaction of Melittin with Phospholipid Bilayers: The Effects of Concentration and Ionic Strength.International journal of molecular sciences · 2020Article
- Membrane Active Peptides Remove Surface Adsorbed Protein Corona From Extracellular Vesicles of Red Blood Cells.Frontiers in chemistry · 2020Article
- Low-coherent optical diffraction tomography by angle-scanning illumination.Journal of biophotonics · 2019Article
- Super-resolution three-dimensional fluorescence and optical diffraction tomography of live cells using structured illumination generated by a digital micromirror device.Scientific reports · 2018Article
- Measurements of three-dimensional refractive index tomography and membrane deformability of live erythrocytes from Pelophylax nigromaculatus.Scientific reports · 2018Article
- Three-dimensional label-free imaging and analysis of Pinus pollen grains using optical diffraction tomography.Scientific reports · 2018Article
- Correlative three-dimensional fluorescence and refractive index tomography: bridging the gap between molecular specificity and quantitative bioimaging.Biomedical optics express · 2017Article
- Identification of non-activated lymphocytes using three-dimensional refractive index tomography and machine learning.Scientific reports · 2017Article
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Here, the actions of melittin, the active molecule of apitoxin or bee venom, were investigated on human red blood cells (RBCs) using quantitative phase imaging techniques. High-resolution real-time 3-D refractive index (RI) measurements and dynamic 2-D phase images of individual melittin-bound RBCs enabled in-depth examination of melittin-induced biophysical alterations of the cells. From the measurements, morphological, intracellular, and mechanical alterations of the RBCs were analyzed quantitatively. Furthermore, leakage of haemoglobin (Hb) inside the RBCs at high melittin concentration was also investigated.
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