Evidence map›Paper›PMID 28839119›Full record

ArticleG3 (Bethesda, Md.)2017

Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in

Adrian J Verster, Erin B Styles, Abigail Mateo, W Brent Derry, Brenda J Andrews, Andrew G Fraser

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Predicting gene essentiality inComputational and structural biotechnology journal · 2020
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adrian J VersterThe Donnelly Centre, University of Toronto, Ontario M5S 1A8, Canada.
Erin B StylesThe Donnelly Centre, University of Toronto, Ontario M5S 1A8, Canada.
Abigail MateoDepartment of Molecular Genetics, University of Toronto, Ontario M5S 1A8, Canada.
W Brent DerryDepartment of Molecular Genetics, University of Toronto, Ontario M5S 1A8, Canada.
Brenda J AndrewsThe Donnelly Centre, University of Toronto, Ontario M5S 1A8, Canada.
Andrew G FraserThe Donnelly Centre, University of Toronto, Ontario M5S 1A8, Canada andyfraser.utoronto@gmail.com.
University of Toronto · CAHospital for Sick Children · CA

Funding

CIHR 137089CIHR 487143CIHR 488367CIHR 97939
6 · The paper itself

Abstract

Genes encoding essential components of core cellular processes are typically highly conserved across eukaryotes. However, a small proportion of essential genes are highly taxonomically restricted; there appear to be no similar genes outside the genomes of highly related species. What are the functions of these poorly characterized taxonomically restricted genes (TRGs)? Systematic screens in

Indexed as

Chromosome SegregationGenes, FungalGenes, HelminthAnimalsCaenorhabditis elegansGene ExpressionHelminth ProteinsProtein Interaction MapsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsHelminth ProteinsSaccharomyces cerevisiae ProteinsCaenorhabditis eleganschromosome segregationSaccharomyces cerevisiae

Identifiers

PMID28839119
PMCPMC5633384
OpenAlexW2747415644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.