Evidence map›Paper›PMID 28839117›Full record

ArticleG3 (Bethesda, Md.)2017

High-Resolution Maps of Mouse Reference Populations.

Petr Simecek, Jiri Forejt, Robert W Williams, Toshihiko Shiroishi, Toyoyuki Takada, Lu Lu, Thomas E Johnson, Beth Bennett, Christian F Deschepper, Marie-Pier Scott-Boyer and 2 more

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Population Genomics of the House Mouse and the Brown Rat.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  6. Born to Cry: A Genetic Dissection of Infant Vocalization.Frontiers in behavioral neuroscience · 2018
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Petr SimecekThe Jackson Laboratory, Bar Harbor, Maine 04609.ORCID 0000-0002-2922-7183
Jiri ForejtDivision Biotechnology and Biomedicine Centre of the Academy of Sciences, Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic, Vestec, Prague 4, 142 20, Czech Republic.
Robert W WilliamsDepartment of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163.
Toshihiko ShiroishiNational Institute of Genetics, Mishima, 411-8540, Japan.
Toyoyuki TakadaNational Institute of Genetics, Mishima, 411-8540, Japan.
Lu LuDepartment of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163.
Thomas E JohnsonUniversity of Colorado at Boulder, Colorado 80309.
Beth BennettUniversity of Colorado at Boulder, Colorado 80309.
Christian F DeschepperInstitut de Recherches Cliniques, Montreal, Quebec, H2W 1R7, Canada.
Marie-Pier Scott-BoyerInstitut de Recherches Cliniques, Montreal, Quebec, H2W 1R7, Canada.
Fernando Pardo-Manuel de VillenaInstitute for Behavioral Genetics, Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina 27599-7264 fernando@med.unc.edu gary.churchill@jax.org.ORCID 0000-0002-5738-5795
Gary A ChurchillThe Jackson Laboratory, Bar Harbor, Maine 04609 fernando@med.unc.edu gary.churchill@jax.org.

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Unlocking Zika Virus Immune Control and Pathogenesis with the Collaborative CrossU19AI100625 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BARIC, RALPH S, HEISE, MARK T · 2012 to 2021
$36.6M
UNC and PERLEGEN, IncP50GM076468 · NIGMS · JACKSON LABORATORY · PI CHESLER, ELISSA J · 2006 to 2015
$31.0M
INIA-STRESS: Informatics and Analysis CoreU01AA016662 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILLIAMS, ROBERT W. · 2007 to 2016
$2.9M
CIHR MOP-93583NCI NIH HHS P30 CA034196NIAAA NIH HHS U01 AA016662NIAID NIH HHS U19 AI100625NIGMS NIH HHS P50 GM076468
6 · The paper itself

Abstract

Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS/IbgTejJ, and C57BL/6J × A/J) and chromosome substitution strain panels (C57BL/6J-Chr#<A/J>, C57BL/6J-Chr#<PWD/Ph>, and C57BL/6J-Chr#<MSM/Ms>). We genotyped all samples using the Affymetrix Mouse Diversity Array with an average intermarker spacing of 4.3 kb. The new genetic maps provide increased precision in the localization of recombination breakpoints compared to the previous maps. Although the strains were presumed to be fully inbred, we found residual heterozygosity in 40% of individual mice from five of the six panels. We also identified

Indexed as

AnimalsChromosome MappingDNA Copy Number VariationsFemaleGenotypeMaleMice, Inbred Strainschromosome substitution strainsgene conversionsmouse diversity genotyping arrayrecombinant inbred strains

Identifiers

PMID28839117
PMCPMC5633391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.