ArticleThe European respiratory journal2017
Clinical and biological characteristics of the French COBRA cohort of adult subjects with asthma.
Article in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Blood eosinophil counts in the general population and airways disease: a comprehensive review and meta-analysis.The European respiratory journal · 2022Pooled it
- Improving machine-learning development in allergology: bridging the gap between open-access and cohort-based databases.Current opinion in allergy and clinical immunology · 2026Review
- Established and Emerging Asthma Biomarkers with a Focus on Biologic Trials: A Narrative Review.Journal of personalized medicine · 2025Review
- Patient education needs in severe asthma, a pilot study.BMC pulmonary medicine · 2024Article
- Severe asthma care trajectories: the French RAMSES cohort.ERJ open research · 2024Article
- Longitudinal follow-up of the asthma status in a French-Canadian cohort.Scientific reports · 2022Article
- The Korean Severe Asthma Registry (KoSAR): real world research in severe asthma.The Korean journal of internal medicine · 2022Review
- Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD.PloS one · 2022Article
- Type 2-high asthma is associated with a specific indoor mycobiome and microbiome.The Journal of allergy and clinical immunology · 2021Article
- Clinical and inflammatory characteristics of patients with asthma in the Spanish MEGA project cohort.Clinical and translational allergy · 2021Article
- Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?BMC medical ethics · 2020Article
- FASE-CPHG study: a panoramic snapshot of difficult-to-treat, severe asthma in French nonacademic hospitals.ERJ open research · 2019Article
- Characteristics of patients with severe, uncontrolled, eosinophilic asthma enrolled in a French cohort.Journal of asthma and allergy · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COhort of BRonchial obstruction and Asthma (COBRA) is a longitudinal cohort that involves 12 French academic institutions. DNA, serum samples and clinical data are collected at entry and every 6 months thereafter.Of 1080 patients with asthma recruited between 2007 and 2015, 401 had mild/moderate and 613 had severe asthma. In cross-sectional analyses, compared with patients with milder disease, patients with severe asthma had more symptoms, exacerbations, hospitalisations and visits to the emergency department during the preceding 12 months, higher numbers of blood eosinophils, and more comorbidities. More than 60% of patients with severe asthma were therapy-uncontrolled at entry, and 152 of them were being treated with omalizumab. In addition, patients with asthma who had the highest eosinophilia levels (>300/mm
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