Evidence map›Paper›PMID 28838956›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2017

Adenylyl Cyclase 1 Is Required for Ethanol-Induced Locomotor Sensitization and Associated Increases in NMDA Receptor Phosphorylation and Function in the Dorsal Medial Striatum.

Kelly E Bosse, Max F Oginsky, Laura L Susick, Sailesh Ramalingam, Carrie R Ferrario, Alana C Conti

Open access · hybridAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Critical Role for GFrontiers in psychiatry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kelly E BosseResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.).
Max F OginskyResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.).
Laura L SusickResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.).
Sailesh RamalingamResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.).
Carrie R FerrarioResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.).
Alana C ContiResearch & Development, John D. Dingell VA Medical Center, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan (K.E.B., L.L.S., S.R., A.C.C.); and Department of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan (M.F.O., C.R.F.) alana.conti@wayne.edu.
John D. Dingell VA Medical Center · USWayne State University · US

Funding

POSTDOCTORAL TRAINING IN THE BIOLOGY OF DRUG ABUSET32DA007268 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI TRAYNOR, JOHN R. · 1991 to 2021
$6.7M
NIDA NIH HHS T32 DA007268
6 · The paper itself

Abstract

Neuroadaptive responses to chronic ethanol, such as behavioral sensitization, are associated with

Indexed as

Adenylyl CyclasesAnimalsCorpus StriatumEthanolExcitatory Postsynaptic PotentialsLocomotionMaleMiceMice, Inbred C57BLMice, KnockoutPhosphorylationReceptors, N-Methyl-D-Aspartateadenylyl cyclase 1Adenylyl CyclasesEthanolNR2B NMDA receptorReceptors, N-Methyl-D-Aspartate

Identifiers

PMID28838956
PMCPMC5625283
OpenAlexW2745703786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.