SynthesisBMJ open2017
Prevalence of depression and depressive symptoms among outpatients: a systematic review and meta-analysis.
Synthesis in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 28 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
207 citing papers in PubMed, 28 syntheses or guidelines pooled it, 483 citations in OpenAlex.
- Physical Activity interventions on health-related quality of life (HR-QoL) in major depressive disorder (MDD): a systematic review and meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2026Pooled it
- Prevalence of depressive symptoms, anxiety, sleep & substance use disorders among older adults in LMICs: A systematic review & meta-analysis.The Indian journal of medical research · 2025Pooled it
- Pooled it
- Clinical efficacy of fecal microbiota transplantation in alleviating depressive symptoms: a meta-analysis of randomized trials.Frontiers in psychiatry · 2025Pooled it
- Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety.Investigative ophthalmology & visual science · 2024Pooled it
- The impact of technology systems and level of support in digital mental health interventions: a secondary meta-analysis.Systematic reviews · 2023Pooled it
- Systematic Review of the Association Between Trauma Severity and Postinjury Symptoms of Depression.World journal of surgery · 2022Pooled it
- TelehealthPsychological medicine · 2022Pooled it
- Apathy and Depression as Predictors of Activities of Daily Living Following Stroke and Traumatic Brain Injuries in Adults: A Meta-Analysis.Neuropsychology review · 2022Pooled it
- Under detection of depression in primary care settings in low and middle-income countries: a systematic review and meta-analysis.Systematic reviews · 2022Pooled it
- Systematic Review for the Medical Applications of Meditation in Randomized Controlled Trials.International journal of environmental research and public health · 2022Pooled it
- The relationship between mental health and risk of active tuberculosis: a systematic review.BMJ open · 2022Pooled it
- The Global Landscape of the Burden of Depressive Symptoms/Major Depression in Individuals Living With HIV/AIDs and Its Effect on Antiretroviral Medication Adherence: An Umbrella Review.Frontiers in psychiatry · 2022Pooled it
- The effect of the COVID-19 pandemic on health care workers' anxiety levels: a meta-analysis.PeerJ · 2022Pooled it
- Pooled it
- Use of Geographic Information Systems to Explore Associations between Neighborhood Attributes and Mental Health Outcomes in Adults: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis.Annals of the New York Academy of Sciences · 2021Pooled it
- The Prevalence of Psychological Status During the COVID-19 Epidemic in China: A Systemic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Seroprevalence of Hepatitis C Viral Infection in Ethiopia: A Systematic Review and Meta-Analysis.TheScientificWorldJournal · 2021Pooled it
- Diabetes in Pregnancy and Risk of Antepartum Depression: A Systematic Review and Meta-Analysis of Cohort Studies.International journal of environmental research and public health · 2020Pooled it
147 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDepression and depressive symptoms are common mental disorders that have a considerable effect on patients' health-related quality of life and satisfaction with medical care, but the prevalence of these conditions varies substantially between published studies. The aim of this study is to conduct a systematic review and meta-analysis to provide a precise estimate of the prevalence of depression or depressive symptoms among outpatients in different clinical specialties.
designSystematic review and meta-analysis. DATA SOURCES AND ELIGIBILITY CRITERIA: The PubMed and PsycINFO, EMBASE and Cochrane Library databases were searched to identify observational studies that contained information on the prevalence of depression and depressive symptoms in outpatients. All studies included were published before January 2016. Data characteristics were extracted independently by two investigators. The point prevalence of depression or depressive symptoms was measured using validated self-report questionnaires or structured interviews. Assessments were pooled using a random-effects model. Differences in study-level characteristics were estimated by meta-regression analysis. Heterogeneity was assessed using standard χ
resultsEighty-three cross-sectional studies involving 41 344 individuals were included in this study. The overall pooled prevalence of depression or depressive symptoms was 27.0% (10 943/41 344 individuals; 95% CI 24.0% to 29.0%), with significant heterogeneity between studies (p<0.0001, τ
conclusionOur study provides evidence that a significant proportion of outpatients experience depression or depressive symptoms, highlighting the importance of developing effective management strategies for the early identification and treatment of these conditions among outpatients in clinical practice. The substantial heterogeneity between studies was not fully explained by the variables examined.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.