Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2017
Cost Offset Associated With Early Start Denver Model for Children With Autism.
Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- Effects of Parent-Implemented Interventions on Outcomes of Children with Autism: A Meta-Analysis.Journal of autism and developmental disorders · 2023Pooled it
- Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2020Pooled it
- Pooled it
- Efficacy and moderating factors of the Early Start Denver Model in Chinese toddlers with autism spectrum disorder: a longitudinal study.World journal of pediatrics : WJP · 2023Trial
- Estimated Therapy Costs and Downstream Cost Consequences of iBASIS-Video Interaction to Promote Positive Parenting Intervention vs Usual Care Among Children Displaying Early Behavioral Signs of Autism in Australia.JAMA network open · 2023Trial
- The potential cost-effectiveness of novel cord blood therapies in children with autism spectrum disorder.PloS one · 2023Trial
- Trial
- Article
- Initial Validation of the Mandarin Translation of the Stanford Social Dimensions Scale (SSDS).Journal of autism and developmental disorders · 2026Article
- Parent Perspectives on Mobile Health Autism Screeners.Journal of autism and developmental disorders · 2026Article
- AI-supported early autism identification as public health infrastructure: economic implications for the United States using a scenario-based economic model.Frontiers in public health · 2026Article
- Exploring social network factors impacting the implementation of communication supports designed for minimally verbal autistic preschool children: a study protocol.BMC pediatrics · 2025Article
- AI-Enabled Technologies and Biomarker Analysis for the Early Identification of Autism and Related Neurodevelopmental Disorders.Children (Basel, Switzerland) · 2025Review
- Delivered Right to Your Own Home: Community Perspectives on Home-Based Kits for Studying Genetic and Environmental Factors Related to Later Autism Diagnosis.Journal of autism and developmental disorders · 2025Article
- Value-Based Care and Accountable Care Organizations: Implications for Early Autism Diagnosis and Access to Quality Care.Behavioral sciences (Basel, Switzerland) · 2025Article
- Accuracy of the Screening Tool for Autism in Toddlers and Young Children in the primary care setting.Autism : the international journal of research and practice · 2025Article
- Internal Consistency of the Serbian Translation of the Stanford Social Dimensions Scale and Association to Strengths and Difficulties Questionnaire Scores in Male and Female Individuals on the Autism Spectrum and Non-autistic Individuals.Journal of autism and developmental disorders · 2024Article
- Using Causative Methods to Determine System-Level Factors Driving the Uptake and Use of Evidence-Based Practices in a Public Early Intervention System.Administration and policy in mental health · 2024Article
- Eye-Tracking Biomarkers and Autism Diagnosis in Primary Care.JAMA network open · 2024Article
- Pediatrician and parental evaluation of child neurodevelopment at 2 years of age.BMC pediatrics · 2024Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo determine the effect of the Early Start Denver Model (ESDM) for treatment of young children with autism on health care service use and costs.
methodWe used data from a randomized trial that tested the efficacy of the ESDM, which is based on developmental and applied behavioral analytic principles and delivered by trained therapists and parents, for 2 years. Parents were interviewed about their children's service use every 6 months from the onset of the intervention to follow-up (age 6 years). The sample for this study consisted of 39 children with autism who participated in the original randomized trial at age 18 to 30 months, and were also assessed at age 6 years. Of this sample, 21 children were in the ESDM group, and 18 children were in the community care (COM) group. Reported services were categorized and costed by applying unit hourly costs. Annualized service use and costs during the intervention and post intervention for the two study arms were compared.
resultsDuring the intervention, children who received the ESDM had average annualized total health-related costs that were higher by about $14,000 than those of children who received community-based treatment. The higher cost of ESDM was partially offset during the intervention period because children in the ESDM group used less applied behavior analysis (ABA)/early intensive behavioral intervention (EIBI) and speech therapy services than children in the comparison group. In the postintervention period, compared with children who had earlier received treatment as usual in community settings, children in the ESDM group used less ABA/EIBI, occupational/physical therapy, and speech therapy services, resulting in significant cost savings in the amount of about $19,000 per year per child.
conclusionCosts associated with ESDM treatment were fully offset within a few years after the intervention because of reductions in other service use and associated costs. CLINICAL TRIAL REGISTRATION INFORMATION: Early Characteristics of Autism; http://clinicaltrials.gov/; NCT0009415.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.