Evidence map›Paper›PMID 28838463›Full record

ArticleTransplantation proceedings2017

Beware Cold Agglutinins in Organ Donors! Ex Vivo Lung Perfusion From an Uncontrolled Donation After Circulatory-Determination-of-Death Donor With a Cold Agglutinin: A Case Report.

A Venkataraman, J W Blackwell, W K Funkhouser, K R Birchard, S E Beamer, W T Simmons, S H Randell, T M Egan

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplantation proceedings, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A VenkataramanDepartment of Surgery, Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina.
J W BlackwellDepartment of Surgery, Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina.
W K FunkhouserDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina.
K R BirchardDepartment of Radiology, University of North Carolina, Chapel Hill, North Carolina.
S E BeamerDepartment of Surgery, Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina.
W T SimmonsDepartment of Surgery, Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina.
S H RandellDepartment of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina.
T M EganDepartment of Surgery, Division of Cardiothoracic Surgery, University of North Carolina, Chapel Hill, North Carolina. Electronic address: Ltxtme@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

CTRIP Ex-vivo perfusion and ventilation of lungs to assess transplant suitabilityRC2HL101641 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EGAN, THOMAS M. · 2009 to 2010
$1.5M
NHLBI NIH HHS RC2 HL101641
6 · The paper itself

Abstract

backgroundWe began to recover lungs from uncontrolled donation after circulatory determination of death to assess for transplant suitability by means of ex vivo lung perfusion (EVLP) and computerized tomographic (CT) scan. Our first case had a cold agglutinin with an interesting outcome. CASE REPORT: A 60-year-old man collapsed at home and was pronounced dead by Emergency Medical Services personnel. Next-of-kin consented to lung retrieval, and the decedent was ventilated and transported. Lungs were flushed with cold Perfadex, removed, and stored cold. The lungs did not flush well. Medical history revealed a recent hemolytic anemia and a known cold agglutinin. Warm nonventilated ischemia time was 51 minutes. O

conclusionsOrgan donors with cold agglutinins may not be suitable owing to the impact of hypothermic preservation.

Indexed as

Lung TransplantationCold IschemiaCryoglobulinsExtracorporeal CirculationHumansLungMaleMiddle AgedOrgan PreservationPerfusionPulmonary ArteryTissue and Organ HarvestingTissue Donorscold agglutininsCryoglobulins

Identifiers

PMID28838463
PMCPMC6034983
OpenAlexW2745415513

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.