Evidence map›Paper›PMID 28838086›Full record

SynthesisEuropean heart journal. Quality of care & clinical outcomes2017

Incidence of myocardial infarction in pregnancy: a systematic review and meta-analysis of population-based studies.

Paul Gibson, Mariam Narous, Tabassum Firoz, Doris Chou, Maria Barreix, Lale Say, Matthew James, WHO Maternal Morbidity Working Group

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European heart journal. Quality of care & clinical outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Pregnancy-related acute myocardial infarction: a review of the recent literature.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Review
  11. Acute Coronary Syndrome in Pregnancy and the Post-Partum Period.Journal of cardiovascular development and disease · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Pregnancy-Associated Myocardial Infarction.Current treatment options in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Paul GibsonDepartments of Medicine and Obstetrics & Gynecology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Mariam NarousDepartment of Cardiac Sciences, University of Calgary, Calgary, AB, Canada.
Tabassum FirozDepartment of Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Doris ChouDepartment of Reproductive Health and Research, World Health Organization, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), 20 Avenue Appia, Geneva 1211, Switzerland.
Maria BarreixDepartment of Reproductive Health and Research, World Health Organization, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), 20 Avenue Appia, Geneva 1211, Switzerland.
Lale SayDepartment of Reproductive Health and Research, World Health Organization, UNDP/UNFPA/UNICEF/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), 20 Avenue Appia, Geneva 1211, Switzerland.
Matthew JamesDepartments of Medicine and Community Health Sciences, O'Brien Institute for Public Health, Libin Cardiovascular Institute of Alberta, Cumming School of Medicine, University of Calgary, AB, Canada.
WHO Maternal Morbidity Working Group
University of Calgary · CAWorld Health Organization · CHBrown University · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

Aims: Cardiac disease is one of the leading causes of indirect maternal death, and myocardial infarction (MI) is one of its most common aetiologies. The objectives of this systematic review and meta-analysis were to characterize the incidence of pregnancy-associated MI (PAMI), as well as the maternal mortality and the case-fatality rates due to PAMI. Methods and results: Articles were obtained by searching electronic databases, bibliographies and conference proceedings with no language or date restrictions. Two reviewers independently selected population-based cohort and case-control studies reporting on incidence, mortality and case-fatality rates for pregnancy-associated MI. Meta-analysis was performed to estimate pooled maternal incidence, mortality and case-fatality rates. Meta-regression was performed to explore heterogeneity. Based on 17 included studies, the pooled incidence of PAMI and maternal mortality from PAMI were 3.34 (2.09-4.58) and 0.20 (0.10-0.29) per 100 000 pregnancies, respectively. The case-fatality rate was 5.03% (3.78-6.27%). Country/region (meta-regression P = 0.006) and years of study (meta-regression P = 0.04) were potential explanations for the observed heterogeneity in the pooled incidence estimates of maternal MI and its associated mortality, with more recent studies and those conducted in the USA revealing the highest rates. Conclusion: This article provides a global estimate of the incidence, mortality rate, and case fatality rate of pregnancy-associated MI. We identified higher rates of PAMI in the USA (relative to Canada and European countries) and rising rates over time. Further research regarding this population is needed, especially given rising maternal age and the increasing prevalence of cardiovascular risk factors.

Indexed as

Population SurveillanceFemaleHumansIncidenceMaternal MortalityMyocardial InfarctionPregnancyPregnancy Complications, CardiovascularPrevalenceRisk FactorsIncidenceMaternalMorbidityMortalityMyocardial infarctionPregnancy

Identifiers

PMID28838086
PMCPMC5862024
OpenAlexW2570101639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.