Evidence map›Paper›PMID 28838077›Full record

ReviewThe Journal of infectious diseases2017

The Unique Microbiology and Molecular Pathogenesis of Mycoplasma genitalium.

Chris L McGowin, Patricia A Totten

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Advances in adhesion-related pathogenesis inFrontiers in microbiology · 2025
    Review
  3. Influence of cervicovaginal microbiota onMicrobial cell (Graz, Austria) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Unveiling the stealthy tactics: mycoplasma's immune evasion strategies.Frontiers in cellular and infection microbiology · 2023
    Review
  14. Frontiers in microbiology · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Chris L McGowinDepartments of 1 Microbiology, Immunology, and Parasitology.
Patricia A TottenDepartments of 3 Medicine (Division of Infectious Diseases).
Louisiana State University Health Sciences Center New Orleans · USUniversity of Washington · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Daniel F Sarpong · 2012 to 2026
$69.1M
Phase Variation in Mycoplasma GenitaliumR21AI109332 · NIAID · UNIVERSITY OF WASHINGTON · PI TOTTEN, PATRICIA A · 2014 to 2015
$425k
Mycoplasma genitalium variation in longitudinally infected menR21AI107402 · NIAID · UNIVERSITY OF WASHINGTON · PI TOTTEN, PATRICIA A · 2013 to 2014
$411k
NIAID NIH HHS HHSN272201300012INIAID NIH HHS R21 AI107402NIAID NIH HHS R21 AI109332NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Mycoplasma genitalium is increasingly appreciated as a common cause of sexually transmitted disease syndromes, including urethritis in men and cervicitis, endometritis, pelvic inflammatory disease, and possibly preterm birth, tubal factor infertility, and ectopic pregnancy in women. Despite these disease associations, which parallel those of Chlamydia trachomatis and Neisseria gonorrhoeae, the mechanisms by which this pathogen elicits inflammation, causes cellular damage, and persists in its only natural host (humans) are unique and are not fully understood. The purpose of this review is to briefly provide a historical background on the discovery, microbiology, and recognition of M. genitalium as a pathogen, and then summarize the recent advances in our understanding of the molecular biology and pathogenesis of this unique urogenital organism. Collectively, the basic scientific discussions herein should provide a framework for understanding the clinical and epidemiological outcomes described in the accompanying articles in this supplemental issue.

Indexed as

Immune EvasionFemaleGenome, BacterialHumansImmunityMaleMycoplasma genitaliumMycoplasma InfectionsRisk FactorsSexually Transmitted Diseases, BacterialUrethritisUterine Cervicitisgenitaliumimmunitymycoplasmarecombinationregulation

Identifiers

PMID28838077
PMCPMC5853509
OpenAlexW2741559868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.