Evidence map›Paper›PMID 28838074›Full record

ReviewThe Journal of infectious diseases2017

Mycoplasma genitalium Infection in Men.

Patrick J Horner, David H Martin

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.

  1. Pooled it
  2. Drug resistance ofFrontiers in cellular and infection microbiology · 2026
    Review
  3. Towards precision management ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical characteristics and symptoms associated withSexually transmitted infections · 2025
    Article
  9. Article
  10. Article
  11. Prevalence ofSexually transmitted infections · 2024
    Article
  12. Prevalence ofOpen forum infectious diseases · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. gyrA Mutations in Mycoplasma genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-Guided Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  19. Antimicrobial agents and chemotherapy · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Patrick J HornerSchool of Social and Community Medicine, University of Bristol.
David H MartinDepartment of Epidemiology, Tulane University School of Public Health.
Louisiana State University Health Sciences Center New Orleans · USPublic Health England · GB

Funding

Trichomonas vaginalis repeat infections among HIV negative womenR01AI097080 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KISSINGER, PATRICIA J · 2012 to 2016
$3.7M
A new approach to controlling chlamydia transmission in young peopleR01HD086794 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI KISSINGER, PATRICIA J · 2016 to 2020
$2.9M
NIAID NIH HHS HHSN272201300012INIAID NIH HHS R01 AI097080NICHD NIH HHS R01 HD086794
6 · The paper itself

Abstract

Mycoplasmagenitalium is one of the major causes of nongonococcal urethritis (NGU) worldwide but an uncommon sexually transmitted infection (STI) in the general population. The risk of sexual transmission is probably lower than for Chlamydia trachomatis. Infection in men is usually asymptomatic and it is likely that most men resolve infection without developing disease. The incubation period for NGU caused by Mycoplasma genitalium is probably longer than for NGU caused by C. trachomatis. The clinical characteristics of symptomatic NGU have not been shown to identify the pathogen specific etiology. Effective treatment of men and their sexual partner(s) is complicated as macrolide antimicrobial resistance is now common in many countries, conceivably due to the widespread use of azithromycin 1 g to treat STIs and the limited availability of diagnostic tests for M. genitalium. Improved outcomes in men with NGU and better antimicrobial stewardship are likely to arise from the introduction of diagnostic M. genitalium nucleic acid amplification testing including antimicrobial resistance testing in men with symptoms of NGU as well as in their current sexual partner(s). The cost effectiveness of these approaches needs further evaluation. The evidence that M. genitalium causes epididymo-orchitis, proctitis, and reactive arthritis and facilitates human immunodeficiency virus transmission in men is weak, although biologically plausible. In the absence of randomized controlled trials demonstrating cost effectiveness, screening of asymptomatic men cannot be recommended.

Indexed as

Anti-Bacterial AgentsAzithromycinDrug Resistance, BacterialFemaleHumansMacrolidesMaleMale Urogenital DiseasesMycoplasma genitaliumMycoplasma InfectionsNucleic Acid Amplification TechniquesSexual PartnersUrethritisAnti-Bacterial AgentsAzithromycinMacrolidesantimicrobial resistancemenMycoplasma genitaliumnongonococcal urethritisnucleic acid amplification test

Identifiers

PMID28838074
PMCPMC5853510
OpenAlexW2740092384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.