ArticlePloS one2017
In silico analysis of protein toxin and bacteriocins from Lactobacillus paracasei SD1 genome and available online databases.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Article
- Efficacy of Lacticaseibacillus rhamnosus probiotic strains in treating chromate induced dermatitis.Scientific reports · 2025Article
- Development of Synthetic Antimicrobial Peptides Based on Genomic Analysis of Streptococcus salivarius.Journal of clinical laboratory analysis · 2025Article
- Bacteriocins from Lactic Acid Bacteria Could Modulate the Wnt Pathway: A Possible Therapeutic Candidate for the Management of Colorectal Cancer- AnAnti-cancer agents in medicinal chemistry · 2025Article
- Genomic Assessment of Potential ProbioticTropical life sciences research · 2024Article
- Probiotic Insights from the Genomic Exploration ofFoods (Basel, Switzerland) · 2024Article
- Unlocking the genetic potential ofHeliyon · 2024Article
- How probiotics, prebiotics, synbiotics, and postbiotics prevent dental caries: an oral microbiota perspective.NPJ biofilms and microbiomes · 2024Review
- Genome Analysis for Cholesterol-Lowing Action and Bacteriocin Production ofMicroorganisms · 2024Article
- Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products.Current genetics · 2023Article
- Distribution of Genes Related to Probiotic Effects Across Lacticaseibacillus rhamnosus Revealed by Population Structure.Probiotics and antimicrobial proteins · 2023Article
- Safety Evaluation of Lactobacillus delbrueckii subsp. lactis CIDCA 133: a Health-Promoting Bacteria.Probiotics and antimicrobial proteins · 2022Article
- Potential Probiotic Strains From Milk and Water Kefir Grains in Singapore-Use for Defense Against Enteric Bacterial Pathogens.Frontiers in microbiology · 2022Article
- Evaluation of probiotic characteristics and whole genome analysis of Pediococcus pentosaceus MR001 for use as probiotic bacteria in shrimp aquaculture.Scientific reports · 2021Article
- Quantification and gene expression ofThe Saudi dental journal · 2021Article
- Genomic Insight intoMicroorganisms · 2020Article
- Safety Assessment of a Nham Starter Culture Lactobacillus plantarum BCC9546 via Whole-genome Analysis.Scientific reports · 2020Article
- Development of Bacterial Therapeutics against the Bovine Respiratory Pathogen Mannheimia haemolytica.Applied and environmental microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lactobacillus paracasei SD1 is a potential probiotic strain due to its ability to survive several conditions in human dental cavities. To ascertain its safety for human use, we therefore performed a comprehensive bioinformatics analysis and characterization of the bacterial protein toxins produced by this strain. We report the complete genome of Lactobacillus paracasei SD1 and its comparison to other Lactobacillus genomes. Additionally, we identify and analyze its protein toxins and antimicrobial proteins using reliable online database resources and establish its phylogenetic relationship with other bacterial genomes. Our investigation suggests that this strain is safe for human use and contains several bacteriocins that confer health benefits to the host. An in silico analysis of protein-protein interactions between the target bacteriocins and the microbial proteins gtfB and luxS of Streptococcus mutans was performed and is discussed here.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.