Evidence map›Paper›PMID 28837616›Full record

ArticlePloS one2017

A novel device for collecting and dispensing fingerstick blood for point of care testing.

Alexis F Sauer-Budge, Samuel J Brookfield, Ronald Janzen, Sarah McGray, Anna Boardman, Holger Wirz, Nira R Pollock

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. Engineering Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Alexis F Sauer-BudgeCenter for Manufacturing Innovation, Fraunhofer USA, Brookline, Massachusetts, United States of America.
Samuel J BrookfieldCenter for Manufacturing Innovation, Fraunhofer USA, Brookline, Massachusetts, United States of America.
Ronald JanzenCenter for Manufacturing Innovation, Fraunhofer USA, Brookline, Massachusetts, United States of America.
Sarah McGrayPATH, Seattle, Washington, United States of America.
Anna BoardmanCenter for Manufacturing Innovation, Fraunhofer USA, Brookline, Massachusetts, United States of America.
Holger WirzCenter for Manufacturing Innovation, Fraunhofer USA, Brookline, Massachusetts, United States of America.
Nira R PollockBoston Children's Hospital/Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America.ORCID http://orcid.org/0000-0002-6396-2915
Fraunhofer USA Center for Manufacturing Innovation · USBoston Children's Hospital · USBoston University · USProgram for Appropriate Technology in Health · US

Funding

Rapid Fluorescence-Based Determination of Antibiotic SusceptibilityU54EB015408 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI PARRISH, JOHN A, SCHACHTER, STEVEN · 2012 to 2022
$49.2M
NIBIB NIH HHS U54 EB015408
6 · The paper itself

Abstract

The increased world-wide availability of point-of-care (POC) tests utilizing fingerstick blood has led to testing scenarios in which multiple separate fingersticks are performed during a single patient encounter, generating cumulative discomfort and reducing testing efficiency. We have developed a device capable of a) collection of up to 100 μL of fingerstick blood from a single fingerstick by capillary action, and b) dispensing this blood in variable increments set by the user. We tested the prototype device both in a controlled laboratory setting and in a fingerstick study involving naive device users, and found it to have accuracy and precision similar to a conventional pipettor. The users also found the device to be easy to use, and recommended minor ergonomic improvements. Our device would allow performance of multiple POC tests from a single fingerstick blood sample, thus providing a novel functionality that may be of use in many testing settings worldwide.

Indexed as

Point-of-Care TestingBlood Specimen CollectionFingersHumans

Identifiers

PMID28837616
PMCPMC5570352
OpenAlexW2747248737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.