ArticlePLoS computational biology2017
From homeostasis to behavior: Balanced activity in an exploration of embodied dynamic environmental-neural interaction.
Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- NDST3-Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The spatial layout of antagonistic brain regions is explicable based on geometric principles.Communications biology · 2025Article
- Computational memory capacity predicts aging and cognitive decline.Nature communications · 2025Article
- Dynamic Ecosystem Adaptation through Allostasis (DEA-A) Model: Conceptual Presentation of an Integrative Theoretical Framework for Global Health Change.International journal of environmental research and public health · 2024Article
- Connectome-based reservoir computing with the conn2res toolbox.Nature communications · 2024Article
- Clinical and Translational Implications of an Emerging Developmental Substructure for Autism.Annual review of clinical psychology · 2021Article
- Advanced Meditation Alters Resting-State Brain Network Connectivity Correlating With Improved Mindfulness.Frontiers in psychology · 2021Article
- Critical synchronization dynamics of the Kuramoto model on connectome and small world graphs.Scientific reports · 2019Article
- Conflicting emergences. Weak vs. strong emergence for the modelling of brain function.Neuroscience and biobehavioral reviews · 2019Review
- A Non-cognitive Behavioral Model for Interpreting Functional Neuroimaging Studies.Frontiers in human neuroscience · 2019Article
- Homeostatic plasticity and emergence of functional networks in a whole-brain model at criticality.Scientific reports · 2018Article
- From State-to-Trait Meditation: Reconfiguration of Central Executive and Default Mode Networks.eNeuroArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
In recent years, there have been many computational simulations of spontaneous neural dynamics. Here, we describe a simple model of spontaneous neural dynamics that controls an agent moving in a simple virtual environment. These dynamics generate interesting brain-environment feedback interactions that rapidly destabilize neural and behavioral dynamics demonstrating the need for homeostatic mechanisms. We investigate roles for homeostatic plasticity both locally (local inhibition adjusting to balance excitatory input) as well as more globally (regional "task negative" activity that compensates for "task positive", sensory input in another region) balancing neural activity and leading to more stable behavior (trajectories through the environment). Our results suggest complementary functional roles for both local and macroscale mechanisms in maintaining neural and behavioral dynamics and a novel functional role for macroscopic "task-negative" patterns of activity (e.g., the default mode network).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.