Evidence map›Paper›PMID 28837402›Full record

ReviewRNA biology2018

tRNA

Jeffery M Tharp, Andreas Ehnbom, Wenshe R Liu

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 56 citations in OpenAlex.

  1. Pyrrolysine supply and demand shapes the translational landscape inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Tuning tRNAs for improved translation.Frontiers in genetics · 2024
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Update of the Pyrrolysyl-tRNA Synthetase/tRNAJournal of bacteriology · 2023
    Review
  17. Ancestral archaea expanded the genetic code with pyrrolysine.The Journal of biological chemistry · 2022
    Article
  18. Review
  19. Directed Evolution ofFrontiers in molecular biosciences · 2022
    Article
  20. Unconventional genetic code systems in archaea.Frontiers in microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeffery M Tharpa Department of Chemistry , Texas A&M University , College Station , TX , USA.
Andreas Ehnboma Department of Chemistry , Texas A&M University , College Station , TX , USA.ORCID 0000-0002-7044-1712
Wenshe R Liua Department of Chemistry , Texas A&M University , College Station , TX , USA.ORCID 0000-0002-7078-6534
Texas A&M University · US

Funding

Studying Reversible Histone Acylations in Nucleosome ContextsR01GM121584 · NIGMS · TEXAS A&M UNIVERSITY · PI LIU, WENSHE RAY · 2017 to 2020
$1.3M
NIGMS NIH HHS R01 GM121584
6 · The paper itself

Abstract

Pyrrolysine is the 22nd proteinogenic amino acid encoded into proteins in response to amber (TAG) codons in a small number of archaea and bacteria. The incorporation of pyrrolysine is facilitated by a specialized aminoacyl-tRNA synthetase (PylRS) and its cognate tRNA (tRNA

Indexed as

Amino Acyl-tRNA SynthetasesCodon, TerminatorEscherichia coliGenetic CodeGenetic EngineeringLysineMethanosarcinaModels, MolecularNucleic Acid ConformationProtein BiosynthesisRNA, TransferAmino Acyl-tRNA SynthetasesCodon, TerminatorLysinepyrrolysineRNA, TransferNon-canonical amino acidspyrrolysinepyrrolysyl-tRNApyrrolysyl-tRNA synthetasesynthetic biologytRNAPyl

Identifiers

PMID28837402
PMCPMC6103707
OpenAlexW2749668525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.