Evidence map›Paper›PMID 28837385›Full record

ReviewChannels (Austin, Tex.)2017

Mechanisms and models of cardiac sodium channel inactivation.

Kathryn E Mangold, Brittany D Brumback, Paweorn Angsutararux, Taylor L Voelker, Wandi Zhu, Po Wei Kang, Jonathan D Moreno, Jonathan R Silva

Abstract readReview
In one paragraph

Review in Channels (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathryn E Mangolda Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Brittany D Brumbacka Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Paweorn Angsutararuxa Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Taylor L Voelkera Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Wandi Zhua Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Po Wei Kanga Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Jonathan D Morenoa Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.
Jonathan R Silvaa Department of Biomedical Engineering , Washington University in St. Louis , St. Louis , MO , USA.

Funding

PRINCIPLES IN CARDIVASCULAR RESEARCH TRAINING PROGRAMT32HL007081 · NHLBI · WASHINGTON UNIVERSITY · PI Abhinav Diwan, Karen Ellen Joynt Maddox · 1985 to 2026
$10.6M
Pediatric Cardiovascular and Pulmonary Research Training Program.T32HL125241 · NHLBI · WASHINGTON UNIVERSITY · PI Juliane Bubeck Wardenburg, Kory J. Lavine · 2015 to 2026
$4.1M
Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
MODULATION OF CARDIAC NAV CHANNEL FUNCTION AND ELECTROPHYSIOLOGY BY INTERACTING MOLECULESR01HL136553 · NHLBI · WASHINGTON UNIVERSITY · PI SILVA, JONATHAN R · 2017 to 2021
$1.9M
Training in Integrative and Systems Biology of Cardiovascular DiseaseT32HL134635 · NHLBI · WASHINGTON UNIVERSITY · PI NERBONNE, JEANNE M. · 2017 to 2021
$1.8M
NHLBI NIH HHS R01 HL136553NHLBI NIH HHS T32 HL007081NHLBI NIH HHS T32 HL125241NHLBI NIH HHS T32 HL134635NIGMS NIH HHS T32 GM099608
6 · The paper itself

Abstract

Shortly after cardiac Na

Indexed as

Models, BiologicalAnimalsHumansMyocytes, CardiacSodium ChannelsSodium Channelscomputational modelsinherited arrhythmiaslate sodium currentsodium channels

Identifiers

PMID28837385
PMCPMC5786193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.