Evidence map›Paper›PMID 28837146›Full record

ArticleCell death & disease2017

Adropin deficiency worsens HFD-induced metabolic defects.

Shi Chen, Kai Zeng, Qi-Cai Liu, Zheng Guo, Sheng Zhang, Xiao-Rong Chen, Jian-Hua Lin, Jun-Ping Wen, Cheng-Fei Zhao, Xin-Hua Lin and 1 more

Abstract readCase Reports
In one paragraph

Article in Cell death & disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Review
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  9. Review
  10. Article
  11. Review
  12. Article
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  14. Review
  15. Role of adropin in arterial stiffening associated with obesity and type 2 diabetes.American journal of physiology. Heart and circulatory physiology · 2022
    Article
  16. Article
  17. Article
  18. Adropin's Role in Energy Homeostasis and Metabolic Disorders.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shi ChenDepartment of Hepatobiliary Surgery, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China.
Kai ZengDepartment of Anesthesiology, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Qi-Cai LiuDepartment of Laboratory Medicine, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Zheng GuoDepartment of Bioinformatics, Fujian Medical University, Fuzhou, China.
Sheng ZhangDepartment of Pathology, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Xiao-Rong ChenDepartment of Radiology, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Jian-Hua LinDepartment of Central Laboratory, 1st Affiliated Hospital, Fuzhou, China.
Jun-Ping WenDepartment of Endocrinology, Fujian Provincial Hospital, Fuzhou, China.
Cheng-Fei ZhaoDepartment of Pharmaceutical Analysis, Putian University, Putian, China.
Xin-Hua LinDepartment of Pharmaceutical Analysis, Fujian Medical University, Fuzhou, China.
Feng GaoDepartment of Pathology, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited efficacy of current treatment methods and increased type 2 diabetes mellitus (T2DM) incidence constitute an incentive for investigating how metabolic homeostasis is maintained, to improve treatment efficacy and identify novel treatment methods. We analyzed a three-generation family of Chinese origin with the common feature of T2DM attacks and fatty pancreas (FP), alongside 19 unrelated patients with FP and 58 cases with T2DM for genetic variations in Enho, serum adropin, and relative T

Indexed as

AnimalsBlood ProteinsDiabetes Mellitus, Type 2Diet, High-FatFemaleHomeostasisHumansIntercellular Signaling Peptides and ProteinsMiceMice, Inbred C57BLMiddle AgedObesityPancreasPeptidesBlood ProteinsEnho protein, humanIntercellular Signaling Peptides and ProteinsPeptides

Identifiers

PMID28837146
PMCPMC5596552

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.