Evidence map›Paper›PMID 28837087›Full record

ArticleNutrients2017

Ginseng Extract G115 Attenuates Ethanol-Induced Depression in Mice by Increasing Brain BDNF Levels.

Weerawan Boonlert, Hattaya Benya-Aphikul, Jariya Umka Welbat, Ratchanee Rodsiri

Abstract readComparative Study
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Phycocyanin alleviates alcohol-induced testicular injury in male Wistar rats.Clinical and experimental reproductive medicine · 2024
    Article
  5. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Effects of Ginseng on Neurological Disorders.Frontiers in cellular neuroscience · 2020
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Ginseng (Nutrients · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weerawan BoonlertDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. one_tsuke@hotmail.com.
Hattaya Benya-AphikulDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. h.benyaaphikul@gmail.com.
Jariya Umka WelbatDepartment of Anatomy, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. jariya@kku.ac.th.
Ratchanee RodsiriDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. ratchanee.r@pharm.chula.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The decrease of brain-derived neurotrophic factor (BDNF) has been reported in alcohol use disorder and major depression. The effective treatment of these comorbid diseases remains undiscovered. Nutraceutical products are therefore proposed as an alternative approach to overcome this challenge. Ginseng extract G115, the standardized extract of

Indexed as

EthanolPanaxAmitriptylineAnimalsAntidepressive AgentsBehavior, AnimalBrain-Derived Neurotrophic FactorDepressionDisease Models, AnimalDose-Response Relationship, DrugHippocampusLocomotionMaleMice, Inbred ICRPhytotherapyPlant ExtractsAmitriptylineAntidepressive AgentsBrain-Derived Neurotrophic FactorEthanolPlant ExtractsBDNFdepressionethanolginseng extract G115micePanax ginseng

Identifiers

PMID28837087
PMCPMC5622691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.