Evidence map›Paper›PMID 28836516›Full record

ArticleEndoscopic ultrasound

Autoimmune pancreatitis: Imaging features.

Yi Dong, Mirko D'Onofrio, Michael Hocke, Christian Jenssen, Andrej Potthoff, Nathan Atkinson, Andre Ignee, Christoph F Dietrich

Abstract read
In one paragraph

Article in Endoscopic ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
  2. Article
  3. Role of endoscopic ultrasound in diagnosis and management of autoimmune pancreatitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Endoscopic diagnosis of immunoglobulin G4-related sclerosing cholangitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Endoscopic Ultrasound (EUS) Guided Elastography.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Basic Pancreatic Lesions: Radiologic-pathologic Correlation.Journal of translational internal medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi DongDepartment of Ultrasound, Zhongshan Hospital, Fudan University, 200032 Shanghai, China.
Mirko D'OnofrioDepartment of Radiology, GB Rossi University Hospital, University of Verona, Verona, Italy.
Michael HockeMedical Department, Helios Klinikum Meiningen, Meiningen, Germany.
Christian JenssenDepartment of Internal Medicine, Krankenhaus Märkisch Oderland, Strausberg, Germany.
Andrej PotthoffDepartment of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany.
Nathan AtkinsonTranslational Gastroenterology Unit, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
Andre IgneeMedical Department, Caritas Krankenhaus, Uhlandstr. 7, D-97980, Bad Mergentheim, Germany.
Christoph F DietrichMedical Department, Caritas Krankenhaus, Uhlandstr. 7, D-97980, Bad Mergentheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesAutoimmune pancreatitis (AIP) remains a difficult disease to diagnose before treatment, particularly if presenting as a focal mass lesion. The purpose of this multicenter retrospective study is to analyze imaging features of histologically confirmed AIP to determine the additional diagnostic value of contrast-enhanced ultrasound (CEUS), contrast-enhanced endoscopic ultrasound (CE-EUS), and elastography to B-mode features. PATIENTS AND

methodsWe report on a retrospective data collection of 60 histologically confirmed cases of AIP in comparison to 16 patients with pancreatic adenocarcinomas (PDAC). All CE (-E) US examinations were assessed by two independent readers in consensus. The role of CEUS and CE-EUS for pancreatic evaluation was defined according to the 2011 European Federation of Societies for Ultrasound in Medicine and Biology guidelines.

resultsAfter injection of ultrasound (US) contrast agents, most AIP lesions displayed focal or diffuse isoenhancement (86.6%) in the arterial phase, while most of the PDAC lesions (93.7%) were hypoenhancing (P < 0.01). During the late phase, most AIP lesions were hyper-(65%) or iso-enhancing (35%), while most PDAC lesions were hypoenhancing (93.7%). CE-EUS was performed in a subset of ten patients and showed hyperenhancement in all AIP cases. Most focal AIP lesions (n = 27, 79.4%) were stiffer than the surrounding pancreatic parenchyma.

conclusionsIn this study, percutaneous and endoscopic contrast enhanced harmonic US techniques consistently revealed diffuse and focal types of AIP to have features consistent with vascularized lesions. Differentiation from the typically hypovascularized pancreatic adenocarcinoma was possible with CE (-E) US evaluation.

Indexed as

Autoimmune pancreatitiscontrast-enhanced endoscopic ultrasoundcontrast-enhanced ultrasoundguideline

Identifiers

PMID28836516
PMCPMC6032703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.