Evidence map›Paper›PMID 28836190›Full record

ReviewBiophysical reviews2017

Lead poisoning: acute exposure of the heart to lead ions promotes changes in cardiac function and Cav1.2 ion channels.

Gonzalo Ferreira de Mattos, Carlos Costa, Florencia Savio, M Alonso, G L Nicolson

Abstract readReview
In one paragraph

Review in Biophysical reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Influence of e-cigarettes and their constituents on cardiac rhythm and arrhythmias.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  3. Article
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  14. Article
  15. Article
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  17. Article
  18. Key Characteristics of Cardiovascular Toxicants.Environmental health perspectives · 2021
    Article
  19. Article
  20. Lead (Pb) exposure and heart failure risk.Environmental science and pollution research international · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gonzalo Ferreira de MattosIon Channels Laboratory, Department of Biophysics, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay. ferreira@fmed.edu.uy.
Carlos CostaIon Channels Laboratory, Department of Biophysics, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay.
Florencia SavioIon Channels Laboratory, Department of Biophysics, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay.
M AlonsoIon Channels Laboratory, Department of Biophysics, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay.
G L NicolsonInstitute for Molecular Medicine, Huntington Beach, CA, USA.
Universidad de la República · UYInstitute for Molecular Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead ions (Pb

Indexed as

Cav1.2 channelsGating currents inactivationIsolated heartLead exposureLead poisoningL-type Ca2+ channels

Identifiers

PMID28836190
PMCPMC5662044
OpenAlexW2750158584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.