Evidence map›Paper›PMID 28836176›Full record

ArticleLa Radiologia medica2017

Elevated hardness of peripheral gland on real-time elastography is an independent marker for high-risk prostate cancers.

Qi Zhang, Jing Yao, Yehua Cai, Limin Zhang, Yishuo Wu, Jingyu Xiong, Jun Shi, Yuanyuan Wang, Yi Wang

Abstract read
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In one paragraph

Article in La Radiologia medica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qi ZhangInstitute of Biomedical Engineering, Shanghai University, Room 803, Xiangying Building, No. 333, Nanchen Rd, Shanghai, 200444, China. zhangq@t.shu.edu.cn.ORCID http://orcid.org/0000-0001-7041-643X
Jing YaoDepartment of Ultrasound, Huashan Hospital, Fudan University, Shanghai, 200438, China.
Yehua CaiDepartment of Ultrasound, Huashan Hospital, Fudan University, Shanghai, 200438, China.
Limin ZhangDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, 200438, China.
Yishuo WuDepartment of Urology, Huashan Hospital, Fudan University, Shanghai, 200438, China.
Jingyu XiongInstitute of Biomedical Engineering, Shanghai University, Room 803, Xiangying Building, No. 333, Nanchen Rd, Shanghai, 200444, China.
Jun ShiInstitute of Biomedical Engineering, Shanghai University, Room 803, Xiangying Building, No. 333, Nanchen Rd, Shanghai, 200444, China.
Yuanyuan WangDepartment of Electronic Engineering, Fudan University, Shanghai, 200433, China.
Yi WangDepartment of Ultrasound, Huashan Hospital, Fudan University, Shanghai, 200438, China.
Fudan University · CNShanghai University · CN

Funding

National Natural Science Foundation of China 61401267National Natural Science Foundation of China 61471231National Natural Science Foundation of China 61671281
6 · The paper itself

Abstract

objectivesTo examine the role of quantitative real-time elastography (RTE) features on differentiation between high-risk prostate cancer (PCA) and non-high-risk prostatic diseases in the initial transperineal biopsy setting.

methodsWe retrospectively included 103 patients with suspicious PCA who underwent both RTE and initial transperineal prostate biopsy. Patients were grouped into high-risk and non-high-risk categories according to the D'Amico's risk stratification. With computer assistance based on MATLAB programming, three features were extracted from RTE, i.e., the median hardness within peripheral gland (PG) (H

resultsForty-seven patients (45.6%) were diagnosed with PCA and 34 (33.0%) were diagnosed with high-risk PCA. Three RTE features were all statistically higher in high-risk PCA than in non-high-risk diseases (p < 0.001), indicating that the PGs in high-risk PCA patients were harder than those in non-high-risk patients. A high H

conclusionsThe elevated hardness of PG identified high-risk PCA and served as an independent marker of high-risk PCA. As a non-invasive imaging modality, the RTE could be potentially used in routine clinical practice for the detection of high-risk PCA to decrease unnecessary biopsies and reduce overtreatment.

Indexed as

AdultAgedAged, 80 and overBiomarkers, TumorBiopsyDiagnosis, DifferentialElasticity Imaging TechniquesHardnessHumansMaleMiddle AgedNeoplasm GradingProstateProstatic NeoplasmsRetrospective StudiesRisk AssessmentBiomarkers, TumorHigh-risk cancersProstate cancer (PCA)Real-time elastography (RTE)Tissue elasticityTransperineal biopsyTransrectal ultrasound (TRUS)

Identifiers

PMID28836176
OpenAlexW2747226742

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.