Evidence map›Paper›PMID 28836059›Full record

ReviewInternational urology and nephrology2017

Posterior reversible encephalopathy syndrome in children with kidney disease.

Cristina Gavrilovici, Ingrith Miron, Luminiţa Voroneanu, Silvia Bădărau, Magdalena Stârcea

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Posterior Reversible Encephalopathy Syndrome, not so Uncommon in Pediatric Patients with Renal Involvement: A Case Series.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cristina Gavrilovici"Sf. Maria" Children's Hospital, Pediatric Department, University of Medicine and Pharmacy "Gr. T. Popa", Iasi, Romania. cristina.gavrilovici2012@gmail.com.
Ingrith Miron"Sf. Maria" Children's Hospital, Pediatric Department, University of Medicine and Pharmacy "Gr. T. Popa", Iasi, Romania.
Luminiţa VoroneanuNephrology Department, "Dr C. I. Parhon" Hospital, University of Medicine and Pharmacy "Gr. T. Popa", Iasi, Romania.
Silvia BădărauNephrology Department, "Dr C. I. Parhon" Hospital, University of Medicine and Pharmacy "Gr. T. Popa", Iasi, Romania.
Magdalena Stârcea"Sf. Maria" Children's Hospital, Pediatric Department, University of Medicine and Pharmacy "Gr. T. Popa", Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible encephalopathy syndrome (PRES) has been described as a neurological condition observed in a variety of clinical settings and is characterized by focal neurological deficits, seizures, headaches, altered mental status, and visual impairment, associated with transient typical lesions on neuroimaging, predominantly in the posterior part of the brain. The most common risk factors for PRES are hypertension, renal diseases, and the use of calcineurin inhibitors. The incidence of PRES in children with renal disorders varies between 4 and 9%, according to different reports. Vasogenic cerebral edema is considered the major pathophysiological mechanism of PRES. There are two main theories regarding the genesis of this edema: (1) hyperperfusion, due to autoregulatory failure of the cerebral vasculature, and (2) hypoperfusion, due to vasoconstriction of the cerebral arteries. In addition, PRES might also be the result of a systemic inflammatory state causing endothelial dysfunction. The management of PRES includes BP control, treatment of seizures, and removal of or reduction in calcineurin inhibitors. Intravenous administration of antihypertensive therapy is preferred, and various drugs have been used in this regard, including nicardipine, labetalol, sodium nitroprusside, and hydralazine. The prognosis of PRES is usually benign, except for rare cases with intracranial hemorrhage.

Indexed as

NeuroimagingCalcineurin InhibitorsDiagnosis, DifferentialHumansKidney DiseasesMagnetic Resonance ImagingPosterior Leukoencephalopathy SyndromeRisk FactorsSteroidsCalcineurin InhibitorsSteroidsChildrenKidney diseasePosterior reversible encephalopathy syndrome

Identifiers

PMID28836059
OpenAlexW2747165818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.