Evidence map›Paper›PMID 28836002›Full record

ArticleJournal of neurology2017

Severe refractory CIDP: a case series of 10 patients treated with bortezomib.

Kalliopi Pitarokoili, Min-Suk Yoon, Ilka Kröger, Anke Reinacher-Schick, Ralf Gold, Christiane Schneider-Gold

Abstract read
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In one paragraph

Article in Journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Mechanisms of Chemotherapy-Induced Neurotoxicity.Frontiers in pharmacology · 2022
    Review
  8. Review
  9. Review
  10. Bortezomib in autoimmune hemolytic anemia and beyond.Therapeutic advances in hematology · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Progress in Hematopoietic Stem Cell Transplantation for CIDP.International journal of medical sciences · 2020
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kalliopi PitarokoiliDepartment of Neurology, St. Josef-Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany. Kalliopi.Pitarokoili@ruhr-uni-bochum.de.ORCID http://orcid.org/0000-0002-2483-4929
Min-Suk YoonDepartment of Neurology, St. Josef-Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.
Ilka KrögerDepartment of Neurology, St. Josef-Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.
Anke Reinacher-SchickDepartment of Hematology and Oncology, St. Josef Hospital, Ruhr University, Bochum, Germany.
Ralf GoldDepartment of Neurology, St. Josef-Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.
Christiane Schneider-GoldDepartment of Neurology, St. Josef-Hospital, Ruhr University, Gudrunstr. 56, 44791, Bochum, Germany.
St. Josef-Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment options for patients with aggressive chronic inflammatory demyelinating neuropathy are limited and include the anti-CD20 antibody rituximab and the immunosuppressive regime cyclophosphamide. We aimed to investigate retrospectively the efficacy of bortezomib, a proteasome inhibitor tackling highly metabolically active cell types such as plasma cells, in a case series of 10 treatment refractory CIDP patients. All patients reported showed a deterioration of the clinical CIDP scores under first-line treatment or escalating treatment with cyclophosphamide or rituximab. One or two cycles of bortezomib treatment (each cycle with 1.3 mg/m

Indexed as

AdultAgedAntigens, CD20Antineoplastic AgentsBortezomibDose-Response Relationship, DrugFemaleFollow-Up StudiesHumansImmunoglobulins, IntravenousMaleMiddle AgedPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingRetrospective StudiesTreatment OutcomeYoung AdultAntigens, CD20Antineoplastic AgentsBortezomibImmunoglobulins, IntravenousB cellsBortezomibChronic inflammatory demyelinating polyneuropathyNerve conduction studiesProteasome inhibitorTreatment

Identifiers

PMID28836002
OpenAlexW2748212067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.