Evidence map›Paper›PMID 28835901›Full record

ArticleJournal of immunology research2017

Beneficial Effects of Prebiotic

D Betty Lew, Christie F Michael, Tracie Overbeck, W Scout Robinson, Erin L Rohman, Jeffrey M Lehman, Jennifer K Patel, Brandi Eiseman, Kim S LeMessurier, Amali E Samarasinghe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. A Functional Bread Fermented withCurrent developments in nutrition · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. BioMed research international · 2018
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

D Betty LewDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.ORCID 0000-0002-0857-5875
Christie F MichaelDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Tracie OverbeckDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
W Scout RobinsonDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Erin L RohmanDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Jeffrey M LehmanDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Jennifer K PatelDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Brandi EisemanDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Kim S LeMessurierDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Amali E SamarasingheDepartment of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
M Waleed GaberDepartment of Pediatrics and Hematology-Oncology, Baylor College of Medicine and Texas Children's Cancer Center, Houston, TX, USA.ORCID 0000-0002-6192-0367
University of Tennessee Health Science Center · USBaylor College of Medicine · US

Funding

Mannan, A Potential Therapeutic for AsthmaR41HL090108 · NHLBI · CUMBERLAND PHARMACEUTICALS, INC. · PI LEW, DUKHEE BETTY · 2009 to 2009
$112k
NHLBI NIH HHS R41 HL090108
6 · The paper itself

Abstract

One of the unmet needs for asthma management is a new therapeutic agent with both anti-inflammatory and anti-smooth muscle (ASM) remodeling effects. The mannose receptor (MR) family plays an important role in allergen uptake and processing of major allergens Der p 1 and Fel d 1. We have previously reported that ASM cells express a mannose receptor (ASM-MR) and that mannan derived from

Indexed as

Airway RemodelingAllergensAnimalsAsthmaCloning, MolecularDisease Models, AnimalHumansLectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorMembrane GlycoproteinsMiceMice, TransgenicMuscle, SmoothPrebioticsAllergensLectins, C-TypeMannansMannose-Binding LectinsMannose ReceptorMembrane GlycoproteinsMRC2 protein, humanPrebioticsReceptors, Cell Surface

Identifiers

PMID28835901
PMCPMC5556605
OpenAlexW2740063972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.