Evidence map›Paper›PMID 28835883›Full record

ArticleAnnals of surgical treatment and research2017

Are prophylactic antibiotics necessary in elective laparoscopic cholecystectomy, regardless of patient risk?

Hyung Jin Kim, Sung Hwa Kang, Young Hoon Roh, Min Chan Kim, Kwan Woo Kim

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgical treatment and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06193837 (Prophylactic Antibiotic in Non-complicated Low Risk Laparoscopic Cholecystectomy; Is it Worthy? A Prospective Randomized Comparative Study.), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06193837 unknown statusnot on this mapstarted 2024, after this paper: background citation

Prophylactic Antibiotic in Non-complicated Low Risk Laparoscopic Cholecystectomy; Is it Worthy? A Prospective Randomized Comparative Study.

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled200ConditionsCholecystectomy, LaparoscopicArmsAugmentin
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyung Jin KimDepartment of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Sung Hwa KangDepartment of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Young Hoon RohDepartment of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Min Chan KimDepartment of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Kwan Woo KimDepartment of Surgery, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea.
Dong-A University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe average rate of surgical site infections (SSIs) for laparoscopic cholecystectomy (LC) has been reported in the literature to be between 0.4% and 6.3%. Also, these recent reviews have concluded that a prophylactic antibiotics for elective LCs in low-risk patients is not useful, but there were no results in high-risk patients.

methodsThe aim of this study was to investigate the role of a single dose of first-generation cephalosporin as a prophylactic antibiotic for patients undergoing elective LC, regardless of patient risk. This randomized clinical trial was conducted from October 2013 to December 2014 by single surgeon at our hospital. Patients were randomized into two groups by following method. Odd-numbered patients (group A) received 1-g cefazolin intravenously within 30 minutes before incision, whereas even-numbered patients (group B) received normal saline intravenously instead of prophylactic antibiotics, with the aim of including 100 patients in each group. SSIs were recorded and compared between the groups.

resultsThere were no differences in preoperative demographics and postoperative findings between the groups. There were no superficial and deep SSIs in either group, 9 cases of superficial seromas developed (4.5%) in the cohort: 4 in group A (4%) and 5 in group B (5%). There were no significant associations between SSIs and the use of prophylactic antibiotics in either group. Additionally, the high-risk group did not show a significantly increased rate of SSIs.

conclusionBased on our study, prophylactic antibiotics are not necessary in elective LC, regardless of patient risk.

Indexed as

Antibiotic prophylaxisLaparoscopic cholecystectomySurgical wound infection

Identifiers

PMID28835883
PMCPMC5566750
OpenAlexW2750045264

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.