Evidence map›Paper›PMID 28835756›Full record

ArticleStem cells international2017

Quality Evaluation of Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair.

Katsunori Shiraishi, Naosuke Kamei, Shunsuke Takeuchi, Shinobu Yanada, Hisashi Mera, Shigeyuki Wakitani, Nobuo Adachi, Mitsuo Ochi

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cartilage regeneration using a novel autologous growth factors-based matrix for full-thickness defects in sheep.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Article
  10. Enrichment of CD146Theranostics · 2019
    Article
  11. The safety and efficacy of magnetic targeting using autologous mesenchymal stem cells for cartilage repair.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Katsunori ShiraishiDepartment of Orthopaedic Surgery, Division of Medicine, Biomedical Sciences Major, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Naosuke KameiDepartment of Orthopaedic Surgery, Division of Medicine, Biomedical Sciences Major, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.ORCID 0000-0001-5076-0145
Shunsuke TakeuchiJapan Tissue Engineering Co., Ltd., Gamagori, Japan.
Shinobu YanadaJapan Tissue Engineering Co., Ltd., Gamagori, Japan.
Hisashi MeraUonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
Shigeyuki WakitaniDepartment of Health and Sports Sciences, Mukogawa Women's University, Nishinomiya, Japan.
Nobuo AdachiDepartment of Orthopaedic Surgery, Division of Medicine, Biomedical Sciences Major, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Mitsuo OchiDepartment of Orthopaedic Surgery, Division of Medicine, Biomedical Sciences Major, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.ORCID 0000-0002-7363-873X
Hiroshima University · JPMukogawa Women's University · JPNiigata University Medical and Dental Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quality evaluation of mesenchymal stem cells (MSCs) based on efficacy would be helpful for their clinical application. In this study, we aimed to find the factors of human bone marrow MSCs relating to cartilage repair. The expression profiles of humoral factors, messenger RNAs (mRNAs), and microRNAs (miRNAs) were analyzed in human bone marrow MSCs from five different donors. We investigated the correlations of these expression profiles with the capacity of the MSCs for proliferation, chondrogenic differentiation, and cartilage repair in vivo. The mRNA expression of

Identifiers

PMID28835756
PMCPMC5556614
OpenAlexW2741417245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.