ArticleMedical science monitor : international medical journal of experimental and clinical research2017
Clinical Characteristics and Prognostic Factors in Bone Metastases from Lung Cancer.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
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Who cites it
70 citing papers in PubMed.
- Development, validation, and visualization of a web-based nomogram for predicting the incidence of leiomyosarcoma patients with distant metastasis.Cancer reports (Hoboken, N.J.) · 2022Trial
- X‑ray FLASH RT inhibits lung cancer bone metastasis via activating CD4⁺ T-cell‑mediated antitumor immunity with modulation of Th17 cell response.Oncoimmunology · 2026Article
- Machine-learning-model based tool for screening bone metastases from lung cancer patients in primary care practice.Journal of orthopaedic surgery and research · 2026Article
- Clinical value of serum osteocalcin (N-MID) combined with thyroid transcription factor-1 for predicting bone metastasis of lung cancer.American journal of cancer research · 2026Article
- Autoantibodies combined with systemic inflammation markers for predicting bone metastases in non-small cell lung cancer patients.Frontiers in immunology · 2026Article
- A Cross-Sectional Study on the Status of Female Lung Cancer Patients With Bone Metastasis With or Without Osteoporosis.Health science reports · 2025Article
- Biomarker-Driven Approaches to Bone Metastases: From Molecular Mechanisms to Clinical Applications.Biomedicines · 2025Review
- Uncommon Manifestations of Lung Cancer: Diagnostic Challenges and Valuable Insights From a Rare Clinical Case.Cureus · 2024Article
- Radiotherapy for hyoid bone metastasis from lung adenocarcinoma: A case report.World journal of clinical oncology · 2024Article
- Predictive value of CA-153, CA-125 and Apo A for ocular metastasis in menopausal female patients with breast cancer.International journal of ophthalmology · 2024Article
- Predictive nomogram for bone metastases in lung cancer based on monocyte infiltration.American journal of cancer research · 2024Article
- Cigarette smoke promotes IL-6-dependent lung cancer migration and osteolytic bone metastasis.International journal of biological sciences · 2024Article
- IncreasedSkeletal radiology · 2023Article
- Chinese expert consensus on the diagnosis and treatment of bone metastasis in lung cancer (2022 edition).Journal of the National Cancer Center · 2023Article
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- Magnetic Resonance Imaging Evaluation of Bone Metastases Treated with Radiotherapy in Palliative Intent: A Multicenter Prospective Study on Clinical and Instrumental Evaluation Assessment Concordance (MARTE Study).Diagnostics (Basel, Switzerland) · 2023Article
- Bone-specific response according to MDA criteria predicts immunotherapy efficacy among advanced non-small cell lung cancer (NSCLC) patients.Journal of cancer research and clinical oncology · 2023Article
- The Role of Immunotherapy or Immuno-Chemotherapy in Non-Small Cell Lung Cancer: A Comprehensive Review.Cancers · 2023Review
- Machine learning in metastatic cancer research: Potentials, possibilities, and prospects.Computational and structural biotechnology journal · 2023Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND This study investigated the prognostic factors of bone metastases from lung cancer. MATERIAL AND METHODS From March 2014 to March 2015, 168 patients with bone metastases from lung cancer treated at our hospital were included and the clinical data were reviewed. The Kaplan-Meier survival curves were calculated and analyzed using the log-rank univariate test. Multivariate regression analysis was conducted using Cox's regression model. RESULTS The overall median survival of the 168 patients was 13 months. The 1-year survival was 54.3% and the 2-year survival was 12.9%. Univariate regression analysis indicated that the pathologic types, number of bone metastases, clinical stage, ECOG scores, and serum ALP levels were significantly correlated with survival (P<0.05). Multivariate regression analysis indicated that the number of bone metastases, clinical stage, and serum ALP levels were significantly correlated with prognosis (P<0.05). The risk associated with multiple bone metastases was 1.72 times of that of single bone metastasis (P=0.029); the risk associated with advanced clinical stage was 1.49 times of that of early clinical stage (P=0.001); and the risk associated with a high serum ALP level was 1.75 times of that of the low serum ALP level (P=0.006). CONCLUSIONS Pathologic types, number of bone metastases, clinical stage, ECOG scores, and serum ALP levels were the prognostic factors for bone metastases from lung cancer.
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