Evidence map›Paper›PMID 28835490›Full record

Observational studyJournal of virology2017

Asymptomatic Primary Infection with Epstein-Barr Virus: Observations on Young Adult Cases.

Rachel J Abbott, Annette Pachnio, Isabela Pedroza-Pacheco, Alison M Leese, Jusnara Begum, Heather M Long, Debbie Croom-Carter, Andrea Stacey, Paul A H Moss, Andrew D Hislop and 3 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 125 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rachel J AbbottInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Annette PachnioInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Isabela Pedroza-PachecoNuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Alison M LeeseInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Jusnara BegumInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Heather M LongInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Debbie Croom-CarterInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
Andrea StaceyNuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Paul A H MossInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Andrew D HislopInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.ORCID http://orcid.org/0000-0002-9521-5295
Persephone BorrowNuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Alan B RickinsonInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Andrew I BellInstitute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom a.i.bell@bham.ac.uk.ORCID http://orcid.org/0000-0001-9520-4417
University of Birmingham · GBUniversity of Oxford · GB

Funding

Cancer Research UK 15032Cancer Research UK C5575/A15032Medical Research Council G.0.9.01755Medical Research Council G0901755Medical Research Council MR/K012037Medical Research Council MR/K012037/1
6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is typically acquired asymptomatically in childhood. In contrast, infection later in life often leads to infectious mononucleosis (IM), a febrile illness characterized by anti-EBV IgM antibody positivity, high loads of circulating latently infected B cells, and a marked lymphocytosis caused by hyperexpansion of EBV-specific CD8

Indexed as

AdultAntibodies, ViralAsymptomatic InfectionsB-LymphocytesCD8-Positive T-LymphocytesDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansKiller Cells, NaturalMalePrognosisProspective StudiesUnited KingdomViral LoadAntibodies, ViralDNA, ViralCD8 T cellEpstein-Barr virushost immune responseinfectious mononucleosisNK cellprimary infection

Identifiers

PMID28835490
PMCPMC5640854
OpenAlexW2746313984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.