Evidence map›Paper›PMID 28835381›Full record

ArticlePediatrics2017

Reliability of Examination Findings in Suspected Community-Acquired Pneumonia.

Todd A Florin, Lilliam Ambroggio, Cole Brokamp, Mantosh S Rattan, Eric J Crotty, Andrea Kachelmeyer, Richard M Ruddy, Samir S Shah

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Factors Associated With Pneumonia Severity in Children: A Systematic Review.Journal of the Pediatric Infectious Diseases Society · 2018
    Pooled it
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  8. Urine Metabolites of Suspected Community-Acquired Pneumonia.The Journal of infectious diseases · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Todd A FlorinDivisions of Emergency Medicine, todd.florin@cchmc.org.
Lilliam AmbroggioDepartment of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.
Cole BrokampBiostatistics and Epidemiology.
Mantosh S RattanDepartment of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.
Eric J CrottyDepartment of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, Ohio.
Andrea KachelmeyerDivisions of Emergency Medicine.
Richard M RuddyDivisions of Emergency Medicine.
Samir S ShahDivisions of Emergency Medicine.
University of Cincinnati Medical Center · USCancer Research And Biostatistics · USCincinnati Children's Hospital Medical Center · US

Funding

Cincinnati Center for Clinical and Translational Sciences and TrainingKL2TR000078 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$1.5M
BIOMARKERS AND RISK STRATIFICATION IN PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIAK23AI121325 · NIAID · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI FLORIN, TODD ADAM · 2016 to 2019
$743k
NCATS NIH HHS KL2 TR000078NIAID NIH HHS K23 AI121325
6 · The paper itself

Abstract

backgroundThe authors of national guidelines emphasize the use of history and examination findings to diagnose community-acquired pneumonia (CAP) in outpatient children. Little is known about the interrater reliability of the physical examination in children with suspected CAP.

methodsThis was a prospective cohort study of children with suspected CAP presenting to a pediatric emergency department from July 2013 to May 2016. Children aged 3 months to 18 years with lower respiratory signs or symptoms who received a chest radiograph were included. We excluded children hospitalized ≤14 days before the study visit and those with a chronic medical condition or aspiration. Two clinicians performed independent examinations and completed identical forms reporting examination findings. Interrater reliability for each finding was reported by using Fleiss' kappa (κ) for categorical variables and intraclass correlation coefficient (ICC) for continuous variables.

resultsNo examination finding had substantial agreement (κ/ICC > 0.8). Two findings (retractions, wheezing) had moderate to substantial agreement (κ/ICC = 0.6-0.8). Nine findings (abdominal pain, pleuritic pain, nasal flaring, skin color, overall impression, cool extremities, tachypnea, respiratory rate, and crackles/rales) had fair to moderate agreement (κ/ICC = 0.4-0.6). Eight findings (capillary refill time, cough, rhonchi, head bobbing, behavior, grunting, general appearance, and decreased breath sounds) had poor to fair reliability (κ/ICC = 0-0.4). Only 3 examination findings had acceptable agreement, with the lower 95% confidence limit >0.4: wheezing, retractions, and respiratory rate.

conclusionsIn this study, we found fair to moderate reliability of many findings used to diagnose CAP. Only 3 findings had acceptable levels of reliability. These findings must be considered in the clinical management and research of pediatric CAP.

Indexed as

AdolescentChildChild, PreschoolCohort StudiesCommunity-Acquired InfectionsDiagnosis, DifferentialEmergency Service, HospitalFemaleHumansInfantMalePhysical ExaminationProspective StudiesReproducibility of Results

Identifiers

PMID28835381
PMCPMC5574720
OpenAlexW2747990130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.