ArticleMolecular biology of the cell2017
Condensin II plays an essential role in reversible assembly of mitotic chromosomes in situ.
Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Mitotic genome folding.The Journal of cell biology · 2025Review
- The Condensin II complex regulates essential gene expression programs during erythropoiesis.Development (Cambridge, England) · 2025Article
- Article
- NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner.Journal of advanced research · 2025Article
- Genome control by SMC complexes.Nature reviews. Molecular cell biology · 2023Review
- Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation.iScience · 2023Article
- Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays.eLife · 2022Article
- Human topoisomerases and their roles in genome stability and organization.Nature reviews. Molecular cell biology · 2022Review
- Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans.Journal of cell science · 2021Article
- Bivalent individualization during chromosome territory formation in Drosophila spermatocytes by controlled condensin II protein activity and additional force generators.PLoS genetics · 2021Article
- Mitotic chromosomes.Seminars in cell & developmental biology · 2021Review
- Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly.Nature communications · 2021Article
- Explore a novel function of human condensins in cellular senescence.Cell & bioscience · 2020Review
- Article
- Condensin complexes: understanding loop extrusion one conformational change at a time.Biochemical Society transactions · 2020Review
- Condensin I is required for faithful meiosis in Drosophila males.Chromosoma · 2020Article
- Computational analysis of morphological and molecular features in gastric cancer tissues.Cancer medicine · 2020Article
- Chromosome disentanglement driven via optimal compaction of loop-extruded brush structures.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Non-SMC condensin I complex subunit H enhances proliferation, migration, and invasion of hepatocellular carcinoma.Molecular carcinogenesis · 2019Article
- Condensins and cohesins - one of these things is not like the other!Journal of cell science · 2019Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Condensins I and II are multisubunit complexes that play a central role in mitotic chromosome assembly. Although both complexes become concentrated along the axial region of each chromatid by metaphase, it remains unclear exactly how such axes might assemble and contribute to chromosome shaping. To address these questions from a physico-chemical point of view, we have established a set of two-step protocols for inducing reversible assembly of chromosome structure in situ, namely within a whole cell. In this assay, mitotic chromosomes are first expanded in a hypotonic buffer containing a Mg
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