Trial reportCirculation2017
Prolonged, Uninterrupted Sedentary Behavior and Glycemic Biomarkers Among US Hispanic/Latino Adults: The HCHS/SOL (Hispanic Community Health Study/Study of Latinos).
Open access · bronzeAbstract readClinical TrialMulticenter Study
In one paragraph
Trial report in Circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.British journal of sports medicine · 2022Pooled it
- Pooled it
- Responsiveness of electromyographically assessed skeletal muscle inactivity: methodological exploration and implications for health benefits.Scientific reports · 2022Trial
- The Effect of a Consumer-Based Activity Tracker Intervention on Accelerometer-Measured Sedentary Time Among Retirees: A Randomized Controlled REACT Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Trial
- Association Between Sedentary Behavior Patterns and Glycemic Outcomes in Women with Overweight and Obesity Under Free-Living Conditions.International journal of behavioral medicine · 2026Article
- Prolonged Short Sleep and Its Effect on Body Weight and Composition : A Pooled Analysis of Randomized Trials.Annals of internal medicine · 2026Observational
- Gene by environment interaction effects on the metabolic subtype of Polycystic Ovary Syndrome in Hispanic Community Health Study/Study of Latinos.Frontiers in genetics · 2026Article
- Characterizing Gray matter atrophy patterns associated with accelerometer-measured sedentary behavior: a population-based study.Brain imaging and behavior · 2025Article
- Movement- and Posture-based Measures of Sedentary Patterns and Associations with Metabolic Syndrome in Hispanic/Latino and non-Hispanic Adults.Journal of racial and ethnic health disparities · 2025Article
- Article
- Sedentary Behavior and Cardiac Events and Mortality After Hospitalization for Acute Coronary Syndrome Symptoms: A Prospective Study.Circulation. Cardiovascular quality and outcomes · 2025Article
- Exploring the Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Hispanic Adolescents with Obesity: A Randomized Crossover Study.Children (Basel, Switzerland) · 2025Article
- Associations of triglyceride glucose-body mass index and the combination of sedentary behavior and physical activity with risks of all-cause mortality and myocardial infarction: a cohort study from the UK biobank.Cardiovascular diabetology · 2025Article
- Metabolome Alterations Associated with Three-Month Sitting-Time Reduction Among Sedentary Postmenopausal Latinas with Cardiometabolic Disease Risk.Metabolites · 2025Article
- Burden of cancer attributable to sedentary behaviour in Germany: an epidemiological analysis of survey data.BMJ open · 2025Article
- Associations between avocado intake and measures of glucose and insulin homeostasis in Hispanic individuals with and without type 2 diabetes: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Nutrition, metabolism, and cardiovascular diseases : NMCD · 2023Article
- Risk Factors for Cardiovascular Disease: Knowledge Gained from the Hispanic Community Health Study/Study of Latinos.Current atherosclerosis reports · 2023Review
- The Impact of Sedentary Behavior on Renal Function Decline in 132,123 Middle Aged and Older Adults: A Nationwide Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- The association of physical activity and sedentary behaviour on health-related quality of life: a cross-sectional study from the physical activity at work (PAW) trial.Journal of activity, sedentary and sleep behaviors · 2023Article
- Determining minimum number of valid days for accurate estimation of sedentary behaviour and awake-time movement behaviours using the ActivPAL3 in nursing home residents.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 1 country.
Keith M DiazFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.). kd2442@columbia.edu.
Jeff GoldsmithFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Heather GreenleeFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Garrett StrizichFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Qibin QiFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Yasmin Mossavar-RahmaniFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Denise C VidotFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Christina BuelnaFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Carrie E BrintzFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Tali ElfassyFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Linda C GalloFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Martha L DaviglusFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Daniela Sotres-AlvarezFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Robert C KaplanFrom Center for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY (K.M.D.); Department of Biostatistics (J.G.) and Department of Epidemiology (H.G.), Mailman School of Public Health, Columbia University, New York, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (G.S., Q.Q., Y.M.-R., R.C.K.); Department of Psychology, University of Miami, Coral Gables, FL (D.C.V., C.E.B.); South Bay Latino Research Center, Graduate School of Public Health (C.B.), and Department of Psychology (L.C.G.), San Diego State University, CA; Department of Epidemiology & Public Health, University of Miami, FL (T.E.); Institute for Minority Health Research, University of Illinois at Chicago (M.L.D.); and Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill (D.S.-A.).
Columbia University Irving Medical Center · USSan Diego State University · USOffice of Minority Health · USUniversity of Miami · USUniversity of Illinois Chicago · US
Funding
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY E. PESSIN · 2015 to 2026
$27.7MCardiometabolic Outcomes in Multi-ethnic Physical Activity & Sedentary Behavior Study (COMPASS)R01HL136266 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAPLAN, ROBERT C, MOSSAVAR-RAHMANI, YASMIN · 2017 to 2020
$3.1MTranslational Research of Negative Emotions and Acute Endothelial DysfunctionR01HL116470 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2013 to 2017
$3.0MThalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6MGENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7MHIV Infection, Metabolites and Subclinical AtherosclerosisK01HL129892 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI QI, QIBIN · 2015 to 2018
$637kHISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–NHLBI NIH HHS K01 HL129892NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL116470NHLBI NIH HHS R01 HL136266NIDDK NIH HHS P30 DK020541
Abstract
backgroundExcessive sedentary time is ubiquitous in developed nations and is associated with deleterious health outcomes. Few studies have examined whether the manner in which sedentary time is accrued (in short or long bouts) carries any clinical relevance. The purpose of this study was to examine the association of prolonged, uninterrupted sedentary behavior with glycemic biomarkers in a cohort of US Hispanic/Latino adults.
methodsWe studied 12 083 participants from the HCHS/SOL (Hispanic Community Health Study/Study of Latinos), a population-based study of Hispanic/Latino adults 18 to 74 years of age. Homeostatic model assessment of insulin resistance and glycosylated hemoglobin were measured from a fasting blood sample, and 2-hour glucose was measured after an oral glucose tolerance test. Sedentary time was objectively measured with a hip-mounted accelerometer. Prolonged, uninterrupted sedentariness was expressed as mean sedentary bout length.
resultsAfter adjustment for potential confounders and moderate to vigorous physical activity, longer sedentary bout duration was dose-dependently associated with increased homeostatic model assessment of insulin resistance (
conclusionsAccruing sedentary time in prolonged, uninterrupted bouts may be deleteriously associated with biomarkers of glucose regulation.
Indexed as
Hispanic or LatinoInsulin ResistanceModels, BiologicalAdolescentAdultAgedBiomarkersBlood GlucoseFemaleGlycated HemoglobinHumansLongitudinal StudiesMaleMiddle AgedSedentary BehaviorBiomarkersBlood GlucoseGlycated HemoglobinepidemiologyexerciseglucoseHispanic Americanssedentary lifestyle
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