Evidence map›Paper›PMID 28835362›Full record

ArticleJournal of the American Heart Association2017

Association Between Acidosis Soon After Reperfusion and Contrast-Induced Nephropathy in Patients With a First-Time ST-Segment Elevation Myocardial Infarction.

Masaomi Gohbara, Azusa Hayakawa, Yusuke Akazawa, Shuta Furihata, Ai Kondo, Yusuke Fukushima, Sakie Tomari, Tsutomu Endo, Kazuo Kimura, Kouichi Tamura

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Masaomi GohbaraDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan gocchi3@hotmail.com.
Azusa HayakawaDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Yusuke AkazawaDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Shuta FurihataDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Ai KondoDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Yusuke FukushimaDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Sakie TomariDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Tsutomu EndoDivision of Cardiology, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan.
Kazuo KimuraDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Kouichi TamuraDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Saiseikai Ibaraki Hospital · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContrast-induced nephropathy (CIN) is associated with poor outcomes in patients with acute myocardial infarction. However, the predictors of CIN have yet to be fully elucidated. METHODS AND

resultsThe study included 273 consecutive patients with a first-time ST-segment elevation myocardial infarction who underwent reperfusion within 12 hours of symptom onset. The exclusion criteria were hemodialysis, mechanical ventilation, or previous coronary artery bypass grafting. All patients underwent arterial blood gas analysis soon after reperfusion. CIN was defined as an increase of 0.5 mg/dL in serum creatinine or a 25% increase from baseline between 48 and 72 hours after contrast medium exposure. Acidosis was defined as an arterial blood pH <7.35. CIN was observed in 35 patients (12.8%). Multivariable logistic regression analysis with forward stepwise algorithm revealed a significant association between CIN and the following: reperfusion time, the prevalence of hypertension, peak creatine kinase-MB, high-sensitivity C-reactive protein on admission, and the incidence of acidosis (

conclusionsThe incidence of acidosis soon after reperfusion was associated with CIN in patients with a first-time ST-segment elevation myocardial infarction.

Indexed as

Acid-Base EquilibriumAcidosisAgedAged, 80 and overBiomarkersBlood Gas AnalysisChi-Square DistributionContrast MediaCreatinineFemaleHospital MortalityHumansIncidenceJapanKidney DiseasesLogistic ModelsBiomarkersContrast MediaCreatinineacidosiscontrast‐induced nephropathyST‐segment elevation myocardial infarction

Identifiers

PMID28835362
PMCPMC5586466
OpenAlexW2747382798

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.