ArticleJournal of biomechanics2017
Loss of ACL function leads to alterations in tibial plateau common dynamic contact stress profiles.
Article in Journal of biomechanics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Alteration of Subchondral Bone Density Distribution Across the Knee Joint Before and After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2026Article
- Individual and Combined Effects of Anterior Cruciate Ligament and Lateral Meniscus Injuries and Surgical Interventions on Tibiofemoral Peak Pressure Magnitude Vary by Flexion Angle.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Effects of kinematic and kinetic variables on articular cartilage mechanical and biological properties.Osteoarthritis and cartilage · 2025Article
- Co-Culture of Mesenchymal Stem Cells and Ligamentocytes on Triphasic Embroidered Poly(L-lactide-co-ε-caprolactone) and Polylactic Acid Scaffolds for Anterior Cruciate Ligament Enthesis Tissue Engineering.International journal of molecular sciences · 2023Article
- Article
- Stress on the posteromedial region of the proximal tibia increased over time after anterior cruciate ligament injury.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- Tekscan analysis programs (TAP) for quantifying dynamic contact mechanics.Journal of biomechanics · 2022Article
- Impediments to Meniscal Repair: Factors at Play Beyond Vascularity.Frontiers in bioengineering and biotechnology · 2022Article
- Microindentation of cartilage before and after articular loading in a bioreactor: assessment of length-scale dependency using two analysis methods.Experimental mechanics · 2021Article
- Cartilage Damage Is Related to ACL Stiffness in a Porcine Model of ACL Repair.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Article
- Osteoarthritis year in review 2018: mechanics.Osteoarthritis and cartilage · 2019Review
- Article
- The Scaffold-Articular Cartilage Interface: A Combined In Vitro and In Silico Analysis Under Controlled Loading Conditions.Journal of biomechanical engineering · 2018Article
- Longitudinal changes in MR T1ρ/T2 signal of meniscus and its association with cartilage T1p/T2 in ACL-injured patients.Osteoarthritis and cartilage · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
It has been suggested that the repetitive nature of altered joint tissue loading which occurs after anterior cruciate ligament (ACL) rupture can contribute to the development of osteoarthritis (OA). However, changes in dynamic knee joint contact stresses after ACL rupture have not been quantified for activities of daily living. Our objective was to characterize changes in dynamic contact stress profiles that occur across the tibial plateau immediately after ACL transection. By subjecting sensor-augmented cadaveric knees to simulated gait, and analyzing the resulting contact stress profiles using a normalized cross-correlation algorithm, we tested the hypothesis that common changes in dynamic contact stress profiles exist after ACL injury. Three common profiles were identified in intact knees, occurring on the: (I) posterior lateral plateau, (II) posterior medial plateau, and (III) central region of the medial plateau. In ACL-transected knees, the magnitude and shape of the common dynamic stress profiles did not change, but their locations on the tibial plateau and the number of knees identified for each profile changed. Furthermore, in the ACL transected knees, a unique common contact stress profile was identified in the posterior region of the lateral plateau near the tibial spine. This framework can be used to understand the regional and temporal changes in joint mechanics after injury.
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Registered trials
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