Evidence map›Paper›PMID 28835282›Full record

ArticleBMC research notes2017

Low plasma vitamin A concentration is associated with tuberculosis in Moroccan population: a preliminary case control study.

Mounia Qrafli, Khalid El Kari, Hassan Aguenaou, Jamal Eddine Bourkadi, Khalid Sadki, Mohammed El Mzibri

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. The Impact of Vitamin A Deficiency on Tuberculosis Progression.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  3. Article
  4. Article
  5. AllCurrent research in immunology · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Changes in Host Response toFrontiers in cellular and infection microbiology · 2019
    Review
  10. Role of Vitamin A in the Immune System.Journal of clinical medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mounia QrafliUnité Mixte de Recherche Nutrition et Alimentation, (CNESTEN-Université Ibn Tofaïl), CNESTEN BP 1382 RP, 10001, Rabat, Morocco.
Khalid El KariUnité Mixte de Recherche Nutrition et Alimentation, (CNESTEN-Université Ibn Tofaïl), CNESTEN BP 1382 RP, 10001, Rabat, Morocco.
Hassan AguenaouUnité Mixte de Recherche Nutrition et Alimentation, (CNESTEN-Université Ibn Tofaïl), CNESTEN BP 1382 RP, 10001, Rabat, Morocco.
Jamal Eddine BourkadiService de Pneumo-Phtisiologie, Hospital Moulay Youssef, CHU Rabat, Rabat, Morocco.
Khalid SadkiLaboratoire de Biochimie-Immunologie, Faculté des Sciences, Rabat, Morocco.
Mohammed El MzibriUnité Mixte de Recherche Nutrition et Alimentation, (CNESTEN-Université Ibn Tofaïl), CNESTEN BP 1382 RP, 10001, Rabat, Morocco. mzibri@yahoo.com.
National Centre for Nuclear Energy, Science and Technology · MAUniversité Ibn-Tofail · MAHôpital El Ayachi · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin A plays numerous roles in immune system. Its deficiency alters both the innate and adaptive immunity. Previous results reported that the micronutrients deficiency, particularly vitamin A, is observed in patients with tuberculosis. Thus, we aimed in this study to assess vitamin A concentrations in Moroccan patients with tuberculosis to set up a large efficacy study of vitamin A supplementation for TB infected patients. Plasma retinol concentration was measured by HPLC in 44 recently diagnosed TB patients and 40 healthy controls.

resultsWe showed that plasma vitamin A is significantly lower in tuberculosis patients as compared to healthy controls (p < 0.0001). Moreover, no significant association was found between vitamin A deficiency and, TB severity and patients' ages.

conclusionOur study confirms the association between low vitamin A levels and tuberculosis disease.

Indexed as

AdolescentAdultCase-Control StudiesFemaleHumansMaleMiddle AgedMoroccoTuberculosisVitamin AVitamin A DeficiencyYoung AdultVitamin ADeficiencyMoroccoPlasmaTuberculosisVitamin A

Identifiers

PMID28835282
PMCPMC5569465
OpenAlexW2747336083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.