Evidence map›Paper›PMID 28834585›Full record

ArticleMedical physics2017

A combined learning algorithm for prostate segmentation on 3D CT images.

Ling Ma, Rongrong Guo, Guoyi Zhang, David M Schuster, Baowei Fei

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ling MaDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Rongrong GuoDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Guoyi ZhangDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
David M SchusterDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Baowei FeiDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USGeorgia Institute of Technology · US

Funding

ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
Multimodality in vivo Molecular Imaging for Prostate PDTR21CA120536 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FEI, BAOWEI · 2006 to 2007
$326k
NCI NIH HHS R01 CA156775NCI NIH HHS R01 CA204254NCI NIH HHS R21 CA120536NCI NIH HHS R21 CA176684
6 · The paper itself

Abstract

purposeSegmentation of the prostate on CT images has many applications in the diagnosis and treatment of prostate cancer. Because of the low soft-tissue contrast on CT images, prostate segmentation is a challenging task. A learning-based segmentation method is proposed for the prostate on three-dimensional (3D) CT images.

methodsWe combine population-based and patient-based learning methods for segmenting the prostate on CT images. Population data can provide useful information to guide the segmentation processing. Because of inter-patient variations, patient-specific information is particularly useful to improve the segmentation accuracy for an individual patient. In this study, we combine a population learning method and a patient-specific learning method to improve the robustness of prostate segmentation on CT images. We train a population model based on the data from a group of prostate patients. We also train a patient-specific model based on the data of the individual patient and incorporate the information as marked by the user interaction into the segmentation processing. We calculate the similarity between the two models to obtain applicable population and patient-specific knowledge to compute the likelihood of a pixel belonging to the prostate tissue. A new adaptive threshold method is developed to convert the likelihood image into a binary image of the prostate, and thus complete the segmentation of the gland on CT images.

resultsThe proposed learning-based segmentation algorithm was validated using 3D CT volumes of 92 patients. All of the CT image volumes were manually segmented independently three times by two, clinically experienced radiologists and the manual segmentation results served as the gold standard for evaluation. The experimental results show that the segmentation method achieved a Dice similarity coefficient of 87.18 ± 2.99%, compared to the manual segmentation.

conclusionsBy combining the population learning and patient-specific learning methods, the proposed method is effective for segmenting the prostate on 3D CT images. The prostate CT segmentation method can be used in various applications including volume measurement and treatment planning of the prostate.

Indexed as

Machine LearningTomography, X-Ray ComputedHumansImaging, Three-DimensionalMaleProstateReference Standardscomputed tomographyimage segmentationpopulation-based learningprostate

Identifiers

PMID28834585
PMCPMC5689097
OpenAlexW2749474653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.