Evidence map›Paper›PMID 28834398›Full record

ArticleCytoskeleton (Hoboken, N.J.)2017

ER/Golgi trafficking is facilitated by unbranched actin filaments containing Tpm4.2.

Anthony J Kee, Nicole S Bryce, Lingyan Yang, Elena Polishchuk, Galina Schevzov, Roberto Weigert, Roman Polishchuk, Peter W Gunning, Edna C Hardeman

Open access · greenAbstract read
In one paragraph

Article in Cytoskeleton (Hoboken, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Actin dynamics in protein homeostasis.Bioscience reports · 2022
    Review
  5. Article
  6. Review
  7. Peptidylglycine α-amidating monooxygenase is required for atrial secretory granule formation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. Actin-tropomyosin distribution in non-muscle cells.Journal of muscle research and cell motility · 2020
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Anthony J KeeSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Nicole S BryceSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Lingyan YangSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Elena PolishchukTelethon Institute of Genetics and Medicine, Naples 80131, Italy.
Galina SchevzovSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Roberto WeigertLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892.
Roman PolishchukTelethon Institute of Genetics and Medicine, Naples 80131, Italy.
Peter W GunningSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Edna C HardemanSchool of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
UNSW Sydney · AUTelethon Institute Of Genetics And Medicine · ITCenter for Cancer Research · US

Funding

Molecular mechanisms of membrane remodelingZIABC011682 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WEIGERT, ROBERTO · 2016 to 2025
$17.5M
Intramural NIH HHS ZIA BC011682
6 · The paper itself

Abstract

We have identified novel actin filaments defined by tropomyosin Tpm4.2 at the ER. EM analysis of mouse embryo fibroblasts (MEFs) isolated from mice expressing a mutant Tpm4.2 (Tpm4

Indexed as

Actin CytoskeletonActinsAnimalsBrefeldin ACell MovementCells, CulturedCytoskeletal ProteinsCytoskeletonEndoplasmic ReticulumFibroblastsGolgi ApparatusHumansMiceMyosin Type IIProtein TransportTropomyosinActinsBrefeldin ACytoskeletal ProteinsMyosin Type IITPM4 protein, humanTropomyosinactin cytoskeletonmembrane traffickingmyosintropomyosin

Identifiers

PMID28834398
PMCPMC7971414
OpenAlexW2748200851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.