ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2018
Correlation between RUST assessments of fracture healing to structural and biomechanical properties.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 58 citations in OpenAlex.
- Callus formation during healing is guided by local strain: a retrospective clinical observation.BMC musculoskeletal disorders · 2026Observational
- PediLocJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Effect of nonsteroidal anti-inflammatory drugs on union, opioid utilization, and pain management for tibial fractures (NSAID Trial): a pragmatic randomized clinical trial protocol.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Combining 3D printing technology with customized metal plates for the treatment of long segment femoral shaft comminuted fractures.Frontiers in surgery · 2026Article
- Correlation between Biochemical Parameters and Radiographic Healing Score in Tibial Fractures.Journal of orthopaedic case reports · 2025Article
- Observational
- Fracture nonunions.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Osseous union after antibiotic cement application with retention of stable orthopaedic hardware in fracture-related infections without union.OTA international : the open access journal of orthopaedic trauma · 2025Article
- Does Fixation Method Affect the Correlation of mRUST and Healing Strength?The Iowa orthopaedic journal · 2025Article
- Transcutaneous COBMC musculoskeletal disorders · 2024Article
- Novel approaches to correlate computerized tomography imaging of bone fracture callus to callus structural mechanics.Bone reports · 2023Article
- Employing direct electromagnetic coupling to assess acute fracture healing: An ovine model assessment.Injury · 2023Article
- Predictors of nonunion for transverse femoral shaft fractures treated with intramedullary nailing: a SIGN database study.OTA international : the open access journal of orthopaedic trauma · 2023Article
- Clinical Assessments of Fracture Healing and Basic Science Correlates: Is There Room for Convergence?Current osteoporosis reports · 2023Review
- Multidisciplinary Treatment of Fracture-Related Infection Has a Positive Impact on Clinical Outcome-A Retrospective Case Control Study at a Tertiary Referral Center.Antibiotics (Basel, Switzerland) · 2023Article
- Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism.Frontiers in dental medicine · 2023Article
- Investigating effects of locally applied boric acid on fracture healing with and without low-level laser therapy.Lasers in medical science · 2022Article
- Low bone mass and impaired fracture healing in mouse models of Trisomy21 (Down syndrome).Bone · 2022Article
- Reliability of Modified Radiographic Union Score for Tibia Scores in the Evaluation of Femoral Shaft Fractures in a Low-resource Setting.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Influence of Thoracic Trauma on Fracture Healing in Long Bones-A Retrospective Analysis.Journal of clinical medicine · 2022Article
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
Radiographic Union Score for Tibia (RUST) and modified RUST (mRUST) are radiographic tools for quantitatively evaluating fracture healing using a cortical scoring system. This tool has high intra-class correlation coefficients (ICCs); however, little evidence has evaluated the scores against the physical properties of bone healing. Closed, stabilized fractures were made in the femora of C3H/HeJ male mice (8-12 week-old) of two dietary groups: A control and a phosphate restricted diet group. Micro-computed tomography (µCT) and torsion testing were carried out at post-operative days (POD) 14, 21, 35, and 42 (n = 10-16) per group time-point. Anteroposterior and lateral radiographic views were constructed from the µCT scans and scored by five raters. The raters also indicated if the fracture were healed. ICCs were 0.71 (mRUST) and 0.63 (RUST). Both RUST scores were positively correlated with callus bone mineral density (BMD) (r = 0.85 and 0.80, p < 0.001) and bone volume fraction (BV/TV) (r = 0.86 and 0.80, p < 0.001). Both RUST scores positively correlated with callus strength (r = 0.35 and 0.26, p < 0.012) and rigidity (r = 0.50 and 0.39, p < 0.001). Radiographically healed calluses had a mRUST ≥13 and a RUST ≥10 and had excellent relationship to structural and biomechanical metrics. Effect of delayed healing due to phosphate dietary restrictions was found at later time points with all mechanical properties (p < 0.011), however no differences found in the RUST scores (p > 0.318). Clinical relevance of this study is both RUST scores showed high correlation to physical properties of healing and generally distinguished healed vs. non-healed fractures. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:945-953, 2018.
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