Evidence map›Paper›PMID 28833469›Full record

ArticleJournal of veterinary internal medicine2017

Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis.

A H Crawford, A L Stoll, D Sanchez-Masian, A Shea, J Michaels, A R Fraser, E Beltran

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 55 citations in OpenAlex.

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  5. Cervical ventroflexion in cats: 86 cases (2003-2024).Journal of feline medicine and surgery · 2025
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  7. Evaluation of the course of improvement with molnupiravir treatment for feline infectious peritonitis.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

A H CrawfordClinical Science and Services, Royal Veterinary College, University of London, Hatfield, Herts, UK.ORCID http://orcid.org/0000-0003-2176-5873
A L StollClinical Science and Services, Royal Veterinary College, University of London, Hatfield, Herts, UK.
D Sanchez-MasianInstitute of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Neston, Cheshire, UK.
A SheaAnimal Health Trust, Kentford, Newmarket, Suffolk, UK.
J MichaelsDepartment of Small Animal Clinical Sciences, University of Tennessee College of Veterinary Medicine, Knoxville, TN.
A R FraserUVet, University of Melbourne, Werribee, Vic., Australia.
E BeltranClinical Science and Services, Royal Veterinary College, University of London, Hatfield, Herts, UK.
University of London · GBAnimal Health Trust · GBMSPCA-Angell · USThe University of Melbourne · AUUniversity of Liverpool · GB

Funding

Department of Health RP-PG-1210-12009
6 · The paper itself

Abstract

backgroundFeline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Information regarding the magnetic resonance imaging (MRI) findings of neurologic FIP currently is limited, resulting in the need for better descriptions to optimize its use as a diagnostic tool.

objectiveTo describe the clinicopathologic features and MRI findings in cases of confirmed neurologic FIP. ANIMALS: Twenty-four client-owned cats with histopathologic confirmation of neurologic FIP.

methodsArchived records from 5 institutions were retrospectively reviewed to identify cases with confirmed neurologic FIP that had undergone antemortem MRI of the CNS. Signalment, clinicopathologic, MRI, and histopathologic findings were evaluated.

resultsThree distinct clinical syndromes were identified: T3-L3 myelopathy (3), central vestibular syndrome (7), and multifocal CNS disease (14). Magnetic resonance imaging abnormalities were detected in all cases, including meningeal contrast enhancement (22), ependymal contrast enhancement (20), ventriculomegaly (20), syringomyelia (17), and foramen magnum herniation (14). Cerebrospinal fluid was analysed in 11 cases; all demonstrated a marked increase in total protein concentration and total nucleated cell count. All 24 cats were euthanized with a median survival time of 14 days (range, 2-115) from onset of clinical signs. Histopathologic analysis identified perivascular pyogranulomatous infiltrates, lymphoplasmacytic infiltrates, or both affecting the leptomeninges (16), choroid plexuses (16), and periventricular parenchyma (13). CONCLUSIONS AND CLINICAL IMPORTANCE: Magnetic resonance imaging is a sensitive means of detecting neurologic FIP, particularly in combination with a compatible signalment, clinical presentation, and CSF analysis.

Indexed as

AnimalsBrainCatsFeline Infectious PeritonitisFemaleMagnetic Resonance ImagingMaleNeuroimagingRetrospective StudiesFeline infectious peritonitisHistopathologyMagnetic resonance imagingNeurologic

Identifiers

PMID28833469
PMCPMC5598904
OpenAlexW2750139931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.