ReviewAnnals of the New York Academy of Sciences2017
Mechanobiology of limb musculoskeletal development.
Review in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin-ATF4 Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cellular Uptake of Nanoparticles is Regulated by Integrin-Based Adhesion to the Extracellular Matrix.ACS applied materials & interfaces · 2026Article
- Chondrogenic Maturation Governs hMSC Mechanoresponsiveness to Dynamic Compression.Bioengineering (Basel, Switzerland) · 2025Article
- Mechanical signal-mediated mitochondria-endoplasmic reticulum contacts modulate Leydig cell testosterone biosynthesis during testis development.Molecular human reproduction · 2025Article
- Review
- Lack of skeletal muscle contraction disrupts fibrous tissue morphogenesis in the developing murine knee.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Equine tendon mechanical behaviour: Prospects for repair and regeneration applications.Veterinary medicine and science · 2023Review
- Time-Dependent Anabolic Response of hMSC-Derived Cartilage Grafts to Hydrostatic Pressure.Journal of tissue engineering and regenerative medicine · 2023Article
- Disrupted development from head to tail: Pervasive effects of postnatal restricted resources on neurobiological, behavioral, and morphometric outcomes.Frontiers in behavioral neuroscience · 2022Article
- A Direct Comparison of Node and Element-Based Finite Element Modeling Approaches to Study Tissue Growth.Journal of biomechanical engineering · 2022Article
- Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Article
- Development and maintenance of tendons and ligaments.Development (Cambridge, England) · 2021Review
- Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue.Science advances · 2021Article
- Interactions between Muscle and Bone-Where Physics Meets Biology.Biomolecules · 2020Review
- EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues.International journal of molecular sciences · 2020Review
- From the perspective of embryonic tendon development: various cells applied to tendon tissue engineering.Annals of translational medicine · 2020Review
- Requirement for scleraxis in the recruitment of mesenchymal progenitors during embryonic tendon elongation.Development (Cambridge, England) · 2019Article
- Embryonic Chicken (Comparative medicine · 2019Review
- Models of tendon development and injury.BMC biomedical engineering · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
While there has been considerable progress in identifying molecular regulators of musculoskeletal development, the role of physical forces in regulating induction, differentiation, and patterning events is less well understood. Here, we highlight recent findings in this area, focusing primarily on model systems that test the mechanical regulation of skeletal and tendon development in the limb. We also discuss a few of the key signaling pathways and mechanisms that have been implicated in mechanotransduction and highlight current gaps in knowledge and opportunities for further research in the field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.