Evidence map›Paper›PMID 28832926›Full record

ArticleJournal of the American Geriatrics Society2017

Thoracic Kyphosis and Physical Function: The Framingham Study.

Amanda L Lorbergs, Joanne M Murabito, Mohamed Jarraya, Ali Guermazi, Brett T Allaire, Laiji Yang, Douglas P Kiel, L Adrienne Cupples, Mary L Bouxsein, Thomas G Travison and 1 more

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. The psychometric properties of the Dubousset Functional Test in patients with thoracic hyperkyphosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. A guide to selecting upper thoracic versus lower thoracic uppermost instrumented vertebra in adult spinal deformity correction.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
  10. The Association Between the Kyphosis Angle and Physical Performance in Community-Dwelling Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  11. Association with sagittal alignment and osteoporosis-related fractures in outpatient women with osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  12. The association between hyperkyphosis and fall incidence among community-dwelling older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  13. Review
  14. Article
  15. Factors Associated With Kyphosis and Kyphosis Progression in Older Men: The MrOS Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  16. Heterogeneity and Spatial Distribution of Intravertebral Trabecular Bone Mineral Density in the Lumbar Spine Is Associated With Prevalent Vertebral Fracture.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  17. Review
  18. A Longitudinal Study of Trunk Muscle Properties and Severity of Thoracic Kyphosis in Women and Men: The Framingham Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amanda L LorbergsInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Joanne M MurabitoSchool of Public Health, Boston University, Boston, Massachusetts.
Mohamed JarrayaMercy Catholic Medical Center, Philadelphia, Pennsylvania.
Ali GuermaziQuantitative Imaging Center, School of Medicine, Boston University, Boston, Massachusetts.
Brett T AllaireCenter for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Laiji YangInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Douglas P KielInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
L Adrienne CupplesSchool of Public Health, Boston University, Boston, Massachusetts.
Mary L BouxseinCenter for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Thomas G TravisonInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.
Elizabeth J SamelsonInstitute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts.

Funding

RISK FACTORS FOR VERTEBRAL FRACTURE AND BONE LOSSR01AR041398 · NIAMS · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI KIEL, DOUGLAS P. · 1991 to 2025
$16.1M
Translational Researchin Aging Trainnig ProgramT32AG023480 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI LIPSITZ, LEWIS · 2004 to 2024
$7.6M
Mechansims and Clinical Importance of Hyperkyphosis:The Framingham StudyR01AG041658 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2011 to 2015
$2.6M
Volumetric Bone Density and Vascular Calcification: The Framingham QCT StudyK01AR053118 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI SAMELSON, ELIZABETH J · 2007 to 2011
$481k
NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INIAMS NIH HHS K01 AR053118NIAMS NIH HHS R01 AR041398NIA NIH HHS R01 AG041658NIA NIH HHS T32 AG023480
6 · The paper itself

Abstract

objectiveTo evaluate the association between thoracic kyphosis and physical function.

designProspective cohort.

settingFramingham, Massachusetts.

participantsFramingham Heart Study Offspring and Third Generation cohort members who had computed tomography (CT) performed between 2002 and 2005 and physical function assessed a mean 3.4 years later (N = 1,100; mean age 61 ± 8, range 50-85). MEASUREMENTS: Thoracic kyphosis (Cobb angle, T4-T12) was measured in degrees using supine CT scout images. Participants were categorized according to Cobb angle to compare those in the highest quartile (Q4, most-severe kyphosis) with those in the lowest quartiles (Q1-Q3). Quick walking speed (m/s), chair-stand time (seconds), grip strength (kg), and self-reported impairments were assessed using standardized procedures. Analyses were adjusted for age, height, weight, smoking, follow-up time, vertebral fractures, and prevalent spinal degeneration.

resultsThoracic kyphosis was not associated with physical function in women or men, and these results were consistent in those younger than 65 and those aged 65 and older. For example, walking speed was similar in adults younger than 65 with and without severe kyphosis (women, Q4: 1.38 m/s, Q1-Q3: 1.40 m/s, P = .69; men, Q4: 1.65 m/s, Q1-Q3: 1.60 m/s; P = .39).

conclusionIn healthy relatively high-functioning women and men, kyphosis severity was not associated with subsequent physical function. Individuals at risk of functional decline cannot be targeted based on supine CT thoracic curvature measures alone.

Indexed as

Disability EvaluationAgedAged, 80 and overExerciseFemaleGeriatric AssessmentHumansKyphosisMaleMiddle AgedProspective StudiesRisk FactorsSupine PositionThoracic VertebraeTomography, X-Ray ComputedWalking Speedagingepidemiologymobilityphysical functionthoracic curvature

Identifiers

PMID28832926
PMCPMC5641235

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.