ArticleHeredity2017
Heritable gene expression differences between lake and stream stickleback include both parallel and antiparallel components.
Article in Heredity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Flexibility in Gene Coexpression at Developmental and Evolutionary Timescales.Molecular biology and evolution · 2025Article
- The interplay between epigenomic and transcriptomic variation during ecotype divergence in stickleback.BMC biology · 2025Article
- Genome-wide analysis of histone modifications can contribute to the identification of candidate cis-regulatory regions in the threespine stickleback fish.BMC genomics · 2024Article
- Genetic assimilation of ancestral plasticity during parallel adaptation to zinc contamination in Silene uniflora.Nature ecology & evolution · 2023Article
- Adapting to climate with limited genetic diversity: Nucleotide, DNA methylation and microbiome variation among populations of the social spider Stegodyphus dumicola.Molecular ecology · 2022Article
- Genetic architecture of repeated phenotypic divergence in Littorina saxatilis ecotype evolution.Evolution; international journal of organic evolution · 2022Article
- Shedding light on the circadian clock of the threespine stickleback.The Journal of experimental biology · 2021Article
- Parallel and population-specific gene regulatory evolution in cold-adapted fly populations.Genetics · 2021Article
- Genetic variation for adaptive traits is associated with polymorphic inversions inEvolution letters · 2021Article
- Article
- A Few Stickleback Suffice for the Transport of Alleles to New Lakes.G3 (Bethesda, Md.) · 2020Article
- A way forward with eco evo devo: an extended theory of resource polymorphism with postglacial fishes as model systems.Biological reviews of the Cambridge Philosophical Society · 2019Review
- Genome-Wide Genotype-Expression Relationships Reveal Both Copy Number and Single Nucleotide Differentiation Contribute to Differential Gene Expression between Stickleback Ecotypes.Genome biology and evolution · 2019Article
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Authors and funding
4 authors.
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Abstract
The repeated phenotypic patterns that characterize populations undergoing parallel evolution provide support for a deterministic role of adaptation by natural selection. Determining the level of parallelism also at the genetic level is thus central to our understanding of how natural selection works. Many studies have looked for repeated genomic patterns in natural populations, but work on gene expression is less common. The studies that have examined gene expression have found some support for parallelism, but those studies almost always used samples collected from the wild that potentially confounds the effects of plasticity with heritable differences. Here we use two independent pairs of lake and stream threespine stickleback (Gasterosteus aculeatus) raised in common garden conditions to assess both parallel and antiparallel (that is, similar versus different directions of lake-stream expression divergence in the two watersheds) heritable gene expression differences as measured by total RNA sequencing. We find that more genes than expected by chance show either parallel (22 genes, 0.18% of expressed genes) or antiparallel (24 genes, 0.20% of expressed genes) lake-stream expression differences. These results correspond well with previous genomic studies in stickleback ecotype pairs that found similar levels of parallelism. We suggest that parallelism might be similarly constrained at the genomic and transcriptomic levels.
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